LAMTOR1

Description		late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Plasma Membrane Late Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Membrane Raft Extracellular Exosome Ragulator Complex Ficolin-1-rich Granule Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Binding Molecular Adaptor Activity
	Biological Process	Regulation Of Cell Growth Regulation Of Receptor Recycling Endosome Organization Lysosome Organization Regulation Of Cholesterol Esterification Regulation Of Cholesterol Efflux Endosomal Transport Positive Regulation Of TOR Signaling Lysosome Localization Cellular Protein Localization Cholesterol Homeostasis Positive Regulation Of MAPK Cascade Regulation Of Catalytic Activity Regulation Of Cholesterol Import Cellular Response To Amino Acid Stimulus
Pathways		Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Neutrophil degranulation Regulation of PTEN gene transcription CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle Amino acids regulate mTORC1
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: ABCF3 CAPN1 CCDC90B CTAG1A CTAG1B EEF1A1 TRIM14
Entrez ID		55004
HPRD ID		07933
Ensembl ID		ENSG00000149357
Uniprot IDs		Q6IAA8
PDB IDs		5X6U 5X6V 5Y39 5Y3A 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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