ACP3 and SHBG

Number of citations of the paper that reports this interaction (PubMedID 15862967)
3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACP3	SHBG
Description		acid phosphatase 3	sex hormone binding globulin
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Lysosome Lysosomal Membrane Cytosol Plasma Membrane Vesicle Membrane Integral Component Of Membrane Filopodium Azurophil Granule Membrane Extracellular Exosome	Extracellular Region Extracellular Exosome
	Molecular Function	Acid Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding 5'-nucleotidase Activity Phosphatase Activity Thiamine Phosphate Phosphatase Activity Identical Protein Binding Protein Homodimerization Activity Lysophosphatidic Acid Phosphatase Activity	Steroid Binding Androgen Binding Protein Binding
	Biological Process	Purine Nucleobase Metabolic Process Thiamine Metabolic Process Lysosome Organization Nucleotide Metabolic Process Dephosphorylation Peptidyl-tyrosine Dephosphorylation Adenosine Metabolic Process Regulation Of Sensory Perception Of Pain Positive Regulation Of Adenosine Receptor Signaling Pathway
Pathways		Neutrophil degranulation
Drugs		(2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid Alpha-Benzyl-Aminobenzyl-Phosphonic Acid Sipuleucel-T	Masoprocol Diethylstilbestrol Levonorgestrel Progesterone Spironolactone Toremifene Estrone Tamoxifen Clomifene Dienestrol Hesperetin Zinc Genistein Naringenin Quercetin 4'-Hydroxyflavanone Afimoxifene Estriol Phenolphthalein Norethynodrel Dioxybenzone Zeranol Gestrinone Equol Zinc acetate Zinc chloride Zinc sulfate, unspecified form Estriol tripropionate
Diseases
GWAS			Androgen levels ( 22936694) Body shape index ( 34021172) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Estradiol levels ( 34255042) Glycated hemoglobin levels ( 34059833) Heel bone mineral density ( 30598549) Hormone measurements ( 24049095) Medication use (calcium channel blockers) ( 31015401) Protein quantitative trait loci ( 18464913) Red cell distribution width ( 27863252) Refractive error ( 32231278) Sex hormone levels ( 26014426) Sex hormone-binding globulin levels ( 22675492 22829776) Testosterone levels ( 21998597) Uterine fibroids ( 31649266) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: EPHB1 ERBB2 SHBG	62 interacting genes: A2M ACP3 ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5F1A AZGP1 C9orf24 CD177 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HDHD5 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A
Entrez ID		55	6462
HPRD ID		01378	01646
Ensembl ID		ENSG00000014257	ENSG00000129214
Uniprot IDs		P15309	B0FWH2 B0FWH8 B4DYU0 I3L145 P04278
PDB IDs		1CVI 1ND5 1ND6 2HPA 2L3H 2L77 2L79 2MG0 3PPD	1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW 6PYA 6PYB 6PYF 6ULB
Enriched GO Terms of Interacting Partners?
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