SHBG and CD177

Number of citations of the paper that reports this interaction (PubMedID 15862967)
3

Data Source:
HPRD (two hybrid)

		SHBG	CD177
Description		sex hormone binding globulin	CD177 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Exosome	Plasma Membrane Lamellipodium Secretory Granule Membrane Specific Granule Membrane Plasma Membrane Raft Anchored Component Of Plasma Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Steroid Binding Androgen Binding Protein Binding	Protease Binding Integrin Binding Protein Binding Calcium-dependent Protein Binding
	Biological Process		Cell Adhesion Leukocyte Cell-cell Adhesion Regulation Of Endocytosis Positive Regulation Of Superoxide Anion Generation Protein Localization To Cell Surface Positive Regulation Of Neutrophil Degranulation Innate Immune Response Cell-cell Junction Maintenance Neutrophil Extravasation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Neutrophil Migration Regulation Of Integrin-mediated Signaling Pathway
Pathways			Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs		Masoprocol Diethylstilbestrol Levonorgestrel Progesterone Spironolactone Toremifene Estrone Tamoxifen Clomifene Dienestrol Hesperetin Zinc Genistein Naringenin Quercetin 4'-Hydroxyflavanone Afimoxifene Estriol Phenolphthalein Norethynodrel Dioxybenzone Zeranol Gestrinone Equol Zinc acetate Zinc chloride Zinc sulfate, unspecified form Estriol tripropionate
Diseases
GWAS		Androgen levels ( 22936694) Body shape index ( 34021172) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Estradiol levels ( 34255042) Glycated hemoglobin levels ( 34059833) Heel bone mineral density ( 30598549) Hormone measurements ( 24049095) Medication use (calcium channel blockers) ( 31015401) Protein quantitative trait loci ( 18464913) Red cell distribution width ( 27863252) Refractive error ( 32231278) Sex hormone levels ( 26014426) Sex hormone-binding globulin levels ( 22675492 22829776) Testosterone levels ( 21998597) Uterine fibroids ( 31649266) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Blood protein levels ( 30072576 29875488)
Interacting Genes		62 interacting genes: A2M ACP3 ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5F1A AZGP1 C9orf24 CD177 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HDHD5 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A	3 interacting genes: EWSR1 KCNIP3 SHBG
Entrez ID		6462	57126
HPRD ID		01646	01222
Ensembl ID		ENSG00000129214	ENSG00000204936
Uniprot IDs		B0FWH2 B0FWH8 B4DYU0 I3L145 P04278	A0A087WVM2 Q8N6Q3
PDB IDs		1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW 6PYA 6PYB 6PYF 6ULB
Enriched GO Terms of Interacting Partners?
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