HPF1 and H1-0

Number of citations of the paper that reports this interaction (PubMedID 28190768)
101

Data Source:
BioGRID (pull down)

		HPF1	H1-0
Description		histone PARylation factor 1	H1.0 linker histone
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GO Annotations	Cellular Component	Chromatin Nucleus Site Of DNA Damage	Chromatin Nucleosome Euchromatin Nucleus Nucleoplasm Golgi Apparatus Actin Cytoskeleton Nuclear Body Transcription Repressor Complex
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Histone Binding Poly-ADP-D-ribose Binding	Minor Groove Of Adenine-thymine-rich DNA Binding Double-stranded DNA Binding RNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding
	Biological Process	Double-strand Break Repair Cellular Response To DNA Damage Stimulus Regulation Of Protein ADP-ribosylation Peptidyl-serine ADP-ribosylation Regulation Of Histone Modification	Negative Regulation Of Transcription By RNA Polymerase II Nucleosome Assembly Gene Silencing Nucleosome Positioning Chromosome Condensation Negative Regulation Of DNA Recombination Positive Regulation Of Transcription Regulatory Region DNA Binding
Pathways			Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: CLCN3 EIF6 FBXO7 H1-0 H1-5 H2BC4 H3-3A H3-4 H3C1 HMGA1 HMGB1 HMGN1 HMGN2 HMGN4 PARP1 PARP2	21 interacting genes: APP CCNE1 CDK1 CDK2 CDK4 CDK5 FBXO7 GRB2 HPF1 IKBKG IPO5 IPO7 KPNA2 KPNB1 NEDD4L NOA1 PARP1 PARP2 PRKCB RAD51B XBP1
Entrez ID		54969	3005
HPRD ID		07924	00819
Ensembl ID		ENSG00000056050	ENSG00000189060
Uniprot IDs		Q9NWY4	P07305
PDB IDs		6M3G 6M3I 6TX2 6TX3 6X0L 6X0M 6X0N	6HQ1 6LA2 6LA8 6LA9 6LAB 6N88 6N89 7DBP 7K5X
Enriched GO Terms of Interacting Partners?
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