NSD3 and SOX3

Number of citations of the paper that reports this interaction (PubMedID 28205554)
52

Data Source:
BioGRID (fluorescent resonance energy transfer)

		NSD3	SOX3
Description		nuclear receptor binding SET domain protein 3	SRY-box transcription factor 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleoplasm
	Molecular Function	Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific) Transcription Regulator Activator Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Central Nervous System Development Sensory Organ Development Sex Determination Anatomical Structure Morphogenesis Hypothalamus Development Pituitary Gland Development Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Face Development
Pathways		PKMTs methylate histone lysines	Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS			Height ( 31562340)
Interacting Genes		49 interacting genes: AKT1 AP3M2 ATM BCAR3 BMP8B CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 E2F5 ESR1 ETV3 ETV6 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 IVNS1ABP LSM1 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 SQSTM1 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557	14 interacting genes: ATXN1 AURKA CDKN2A CRX DACH1 GLIS1 GLIS2 MYC NF2 NFIC NSD3 PAX6 TEAD2 TERT
Entrez ID		54904	6658
HPRD ID		06155	02432
Ensembl ID		ENSG00000147548	ENSG00000134595
Uniprot IDs		Q9BZ95	P41225
PDB IDs		2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR
Enriched GO Terms of Interacting Partners?
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