TTC19 and UBA1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		TTC19	UBA1
Description		tetratricopeptide repeat domain 19	ubiquitin like modifier activating enzyme 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome	Heterochromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Lysosomal Membrane Cytosol Endosome Membrane Desmosome Rough Endoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding Ubiquitin Activating Enzyme Activity Protein Binding ATP Binding
	Biological Process	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly	Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Protein Ubiquitination Protein Modification By Small Protein Conjugation
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs			Hexatantalum Dodecabromide Quercetin
Diseases
GWAS
Interacting Genes		45 interacting genes: AGXT ALK APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688	52 interacting genes: ABCF1 BUB3 CDC34 CDK1 CHEK1 ECHS1 GAN GRB2 HGS HSPH1 LINC01554 MGMT MTNR1A OGT PIAS3 SEMA3F SMAD5 SUMO2 TAF9 TMCC2 TSSC4 TTC19 UBC UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2G2 UBE2H UBE2J1 UBE2J2 UBE2K UBE2L1 UBE2L3 UBE2L6 UBE2M UBE2N UBE2Q2 UBE2R2 UBE2S UBE2T UBE2U UBE2W UBE2Z UBTD2
Entrez ID		54902	7317
HPRD ID		07899	02440
Ensembl ID		ENSG00000011295	ENSG00000130985
Uniprot IDs		A0A024RD83 Q6DKK2	A0A024R1A3 P22314
PDB IDs			4P22 6DC6
Enriched GO Terms of Interacting Partners?
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