GIPC2 and PLEKHA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GIPC2	PLEKHA2
Description		GIPC PDZ domain containing family member 2	pleckstrin homology domain containing A2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome	Nucleus Cytoplasm Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Fibronectin Binding Protein Binding Lipid Binding PDZ Domain Binding Laminin Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Biological_process	Positive Regulation Of Cell-matrix Adhesion
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Body mass index ( 29273807) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) End-stage kidney disease ( 31178898) Hand grip strength ( 29691431) Height ( 20881960 25282103) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean corpuscular hemoglobin concentration ( 32888494) Platelet distribution width ( 32888494) Post bronchodilator FEV1 ( 26634245) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Severe influenza A (H1N1) infection ( 26379185)	High density lipoprotein cholesterol levels ( 31211820) Monocyte percentage of white cells ( 32888494)
Interacting Genes		14 interacting genes: CTRC FZD3 IGSF21 IRF4 LZTS2 PATJ PLEKHA2 PTN SETDB1 SP100 UBE2I UNC119 ZBTB26 ZCCHC7	19 interacting genes: COG6 DLG2 DLG3 EGLN3 FHL5 GIPC1 GIPC2 GIPC3 GOLGA2 HSF2BP KANK2 LNX1 M1AP MPDZ PLEKHA1 PTPN13 SNTG1 TEPSIN TRIM23
Entrez ID		54810	59339
HPRD ID		17040
Ensembl ID		ENSG00000137960	ENSG00000169499
Uniprot IDs		A0A384P5H2 Q8TF65	A0A087WZ32 A8K727 Q9HB19
PDB IDs		3GGE
Enriched GO Terms of Interacting Partners?
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