CTSA and TMEM35A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CTSA	TMEM35A
Description		cathepsin A	transmembrane protein 35A
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosome Endoplasmic Reticulum Membrane Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Lumenal Side Of Lysosomal Membrane	Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Cytoplasmic Vesicle
	Molecular Function	Carboxypeptidase Activity Serine-type Carboxypeptidase Activity Enzyme Activator Activity	Protein Binding Acetylcholine Receptor Regulator Activity
	Biological Process	Proteolysis Intracellular Protein Transport Regulation Of Protein Stability Regulation Of Catalytic Activity Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Chaperone-mediated Autophagy	Chaperone-mediated Protein Complex Assembly Positive Regulation Of Protein Localization To Cell Surface
Pathways		Glycosphingolipid metabolism MHC class II antigen presentation Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation
Drugs
Diseases
GWAS
Interacting Genes		45 interacting genes: AHNAK2 AQP2 AQP6 ARL13B ASPH BSND CD79A COQ9 CPLX4 CREB3L1 CSPG5 ERGIC3 FAM209A FKBP7 FNDC9 GLB1 GORAB HIBADH LAMP2 LMNA LTB4R2 MFSD14B MGST3 MUC1 MYG1 NEU1 PSCA REEP4 RHBDD1 RNF122 SAR1A SGMS2 SIGLEC12 SLC18A1 SLC30A2 SPN SSMEM1 STX2 THAP4 TMEM139 TMEM154 TMEM237 TMEM31 TMEM35A TMX2	32 interacting genes: ADIPOQ APP BET1 C16orf92 CMTM5 COX20 CTSA CXCL16 CYB5B EHHADH FXYD6 GIMAP1 GOSR2 LNPEP MGLL ORMDL1 RTP2 RUSF1 THBD TMEM106C TMEM120A TMEM14C TMEM201 TMEM222 TMEM229B TMEM243 TMEM42 TRIM55 TRIM63 VAMP1 VAMP3 VAPA
Entrez ID		5476	59353
HPRD ID		02020	06523
Ensembl ID		ENSG00000064601	ENSG00000126950
Uniprot IDs		B4E324 P10619 X6R5C5 X6R8A1	Q53FP2
PDB IDs		1IVY 3BP4 3BP7 3BXN 4AZ0 4AZ3 4CI9 4CIA 4CIB 4MWS 4MWT 6WIA
Enriched GO Terms of Interacting Partners?
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