TMEM35A and LNPEP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM35A	LNPEP
Description		transmembrane protein 35A	leucyl and cystinyl aminopeptidase
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Cytoplasmic Vesicle	Extracellular Region Cytoplasm Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Early Endosome Lumen
	Molecular Function	Protein Binding Acetylcholine Receptor Regulator Activity	Aminopeptidase Activity Protein Binding Metallopeptidase Activity Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity
	Biological Process	Chaperone-mediated Protein Complex Assembly Positive Regulation Of Protein Localization To Cell Surface	Protein Polyubiquitination Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Signal Transduction Cell-cell Signaling Female Pregnancy Regulation Of Blood Pressure Peptide Catabolic Process Negative Regulation Of Cold-induced Thermogenesis
Pathways			Endosomal/Vacuolar pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Ankylosing spondylitis ( 23749187) Birdshot chorioretinopathy ( 24957906) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)
Interacting Genes		32 interacting genes: ADIPOQ APP BET1 C16orf92 CMTM5 COX20 CTSA CXCL16 CYB5B EHHADH FXYD6 GIMAP1 GOSR2 LNPEP MGLL ORMDL1 RTP2 RUSF1 THBD TMEM106C TMEM120A TMEM14C TMEM201 TMEM222 TMEM229B TMEM243 TMEM42 TRIM55 TRIM63 VAMP1 VAMP3 VAPA	32 interacting genes: AGT AQP6 ASGR2 CGRRF1 CTAG1A CTAG1B FAM210B FATE1 FCER1G FHOD1 GGT7 GPR42 GPX8 LCN2 LHFPL5 MMGT1 REEP4 REL SLC2A4 SLC35E3 SLC39A9 SMAD9 SSMEM1 STOM TAS2R19 TCF4 TLCD4 TMEM35A TNKS TNKS2 UBQLN1 UNC93A
Entrez ID		59353	4012
HPRD ID		06523	01041
Ensembl ID		ENSG00000126950	ENSG00000113441
Uniprot IDs		Q53FP2	Q9UIQ6
PDB IDs			4P8Q 4PJ6 4Z7I 5C97 5JHQ 5MJ6
Enriched GO Terms of Interacting Partners?
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