GAR1 and LARP7

Number of citations of the paper that reports this interaction (PubMedID 26725010)
53

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		GAR1	LARP7
Description		GAR1 ribonucleoprotein	La ribonucleoprotein 7, transcriptional regulator
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Fibrillar Center Nucleoplasm Telomerase Holoenzyme Complex Box H/ACA SnoRNP Complex Box H/ACA ScaRNP Complex Box H/ACA Telomerase RNP Complex	Nucleus Nucleoplasm Cytosol 7SK SnRNP Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Box H/ACA SnoRNA Binding Telomerase RNA Binding	RNA Binding Protein Binding U6 SnRNA Binding 7SK SnRNA Binding
	Biological Process	SnoRNA Guided RRNA Pseudouridine Synthesis Telomere Maintenance Via Telomerase	Negative Regulation Of Transcription By RNA Polymerase II Box C/D RNA 3'-end Processing MRNA Processing Spermatogenesis RNA Splicing Cell Differentiation Negative Regulation Of Viral Transcription Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of SnRNA Transcription By RNA Polymerase II U6 2'-O-snRNA Methylation
Pathways		Telomere Extension By Telomerase rRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS			Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Dental caries (decayed and filled deciduous teeth) ( 31533690) Meat-related diet ( 32066663) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		4 interacting genes: LARP7 NEAT1 SMN1 SMN2	89 interacting genes: APP BARD1 BRCA1 CHRNB4 GABRG2 GAR1 JMJD6 LRRK2 MCUB MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OSTC PAPSS1 PPA2 PRPF40A PUF60 RN7SK RRH SMS ZGRF1
Entrez ID		54433	51574
HPRD ID		07569	17095
Ensembl ID		ENSG00000109534	ENSG00000174720
Uniprot IDs		Q9NY12	Q4G0J3
PDB IDs			4WKR 5KNW 6D12
Enriched GO Terms of Interacting Partners?
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