LARP7 and PAPSS1

		LARP7	PAPSS1
Description		La ribonucleoprotein 7, transcriptional regulator	3'-phosphoadenosine 5'-phosphosulfate synthase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol 7SK SnRNP Ribonucleoprotein Complex	Cytosol
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding 7SK SnRNA Binding	Adenylylsulfate Kinase Activity Sulfate Adenylyltransferase (ATP) Activity ATP Binding Nucleotidyltransferase Activity Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Box C/D RNA 3'-end Processing MRNA Processing Spermatogenesis RNA Splicing Cell Differentiation Negative Regulation Of Viral Transcription Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of SnRNA Transcription By RNA Polymerase II U6 2'-O-snRNA Methylation	Sulfate Assimilation Skeletal System Development Phosphorylation 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process
Pathways			Transport and synthesis of PAPS Metabolism of ingested H2SeO4 and H2SeO3 into H2Se Signaling by BRAF and RAF1 fusions
Drugs			Adenosine-5'-diphosphate-2',3'-vanadate Adenosine 5'-phosphosulfate Glycerin
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Dental caries (decayed and filled deciduous teeth) ( 31533690) Meat-related diet ( 32066663) Subcortical volume (MOSTest) ( 32665545)	Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Telomere length ( 24478790)
Interacting Genes		89 interacting genes: APP BARD1 BRCA1 CHRNB4 GABRG2 GAR1 JMJD6 LRRK2 MCUB MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OSTC PAPSS1 PPA2 PRPF40A PUF60 RN7SK RRH SMS ZGRF1	5 interacting genes: EEF1A1 ERRFI1 LARP7 PPP1R16A UNC119
Entrez ID		51574	9061
HPRD ID		17095	09132
Ensembl ID		ENSG00000174720	ENSG00000138801
Uniprot IDs		Q4G0J3	O43252
PDB IDs		4WKR 5KNW 6D12	1X6V 1XJQ 1XNJ 2OFW 2OFX 2PEY 2PEZ 2QJF
Enriched GO Terms of Interacting Partners?
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