FXYD6 and RHCG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FXYD6	RHCG
Description		FXYD domain containing ion transport regulator 6	Rh family C glycoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Sodium Channel Regulator Activity	Protein Binding Ammonium Transmembrane Transporter Activity Ankyrin Binding Identical Protein Binding
	Biological Process	Ion Transport Biological_process Regulation Of Sodium Ion Transmembrane Transporter Activity	Cellular Ion Homeostasis Regulation Of PH Ammonium Transport Amine Transport Epithelial Cell Differentiation Homeostatic Process Transepithelial Ammonium Transport Ammonium Transmembrane Transport
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Rhesus glycoproteins mediate ammonium transport.
Drugs
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)	Body size at age 10 ( 32376654) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
Interacting Genes		65 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35C2 SLC35E1 SLC35E3 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119	14 interacting genes: C1QL4 C4orf3 CXCL9 EFNA5 ERMP1 FXYD6 GPR25 IGFBP5 MS4A13 TMEM60 TMEM97 TRARG1 UPK1B YIPF6
Entrez ID		53826	51458
HPRD ID		09456	16102
Ensembl ID		ENSG00000137726	ENSG00000140519
Uniprot IDs		A0A024R3J8 Q9H0Q3	Q9UBD6
PDB IDs			3HD6
Enriched GO Terms of Interacting Partners?
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