PLOD2 and CENPF

		PLOD2	CENPF
Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	centromere protein F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane Extracellular Exosome	Chromosome, Centromeric Region Kinetochore Chromatin Spindle Pole Outer Kinetochore Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Axoneme Nuclear Matrix Midbody Ciliary Basal Body Pronucleus Perinuclear Region Of Cytoplasm Ciliary Transition Fiber
	Molecular Function	Iron Ion Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity	Chromatin Binding Protein Binding Microtubule Binding Protein C-terminus Binding Protein Homodimerization Activity Dynein Complex Binding DNA-binding Transcription Factor Binding
	Biological Process	Response To Hypoxia Cellular Protein Modification Process Protein O-linked Glycosylation Peptidyl-lysine Hydroxylation Hydroxylysine Biosynthetic Process	Mitotic Cell Cycle Kidney Development Chromosome Segregation Mitotic Spindle Assembly Checkpoint Signaling Muscle Organ Development Response To Xenobiotic Stimulus Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Striated Muscle Tissue Development Ventricular System Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Cell Division Metaphase Plate Congression Kinetochore Assembly DNA Biosynthetic Process
Pathways		Collagen biosynthesis and modifying enzymes	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Polo-like kinase mediated events Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs		Ascorbic acid
Diseases
GWAS		Height ( 31562340) Obesity-related traits ( 23251661) Squamous cell lung carcinoma ( 28604730) Zinc levels ( 26025379)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Lung function (FVC) ( 30061609) Response to antineoplastic agents ( 21659360) Serum immune biomarker levels ( 32066700)
Interacting Genes		7 interacting genes: CENPF CLSTN2 LINC01554 LITAF LYPLA1 NUCB1 WWTR1	16 interacting genes: BRAP CENPE CHMP2B FNTA FNTB HSD11B1 IRF6 KLHL41 NDEL1 NUP133 PLOD2 SLC30A1 SLC4A1AP SNAP25 SVIL TOP3B
Entrez ID		5352	1063
HPRD ID		03519	02582
Ensembl ID		ENSG00000152952	ENSG00000117724
Uniprot IDs		O00469	P49454
PDB IDs
Enriched GO Terms of Interacting Partners?
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