PHF1 and BRD2

		PHF1	BRD2
Description		PHD finger protein 1	bromodomain containing 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Site Of Double-strand Break	Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Transcription Corepressor Binding DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding Identical Protein Binding Metal Ion Binding Histone Methyltransferase Binding	Chromatin Binding Protein Serine/threonine Kinase Activity Protein Binding Lysine-acetylated Histone Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation	Neural Tube Closure Nucleosome Assembly Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Spermatogenesis
Pathways		PRC2 methylates histones and DNA	RUNX3 regulates p14-ARF
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Refractive error ( 32231278)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 28008999) Feeling nervous ( 29500382) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 28008999) Ulcerative colitis ( 28008999)
Interacting Genes		78 interacting genes: ABI2 ARID5A ARRDC3 ATXN7L1 AVPI1 BHLHB9 BHLHE40 BIRC7 BOLL BRD2 C11orf49 CALCOCO2 DISC1 DPF1 DYSF EFHC2 EZH2 FHL2 FOSB GOLGA6L9 GPKOW H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C6 H3C7 H3C8 H4C1 HOMEZ HSD17B14 INCA1 IRAK1BP1 KIAA0408 KRT40 LBX1 LZTS2 MAGED1 MDFI MEOX2 MORN3 NAB2 NEK6 PATZ1 PDLIM7 PFDN5 PIBF1 PRR20A PRR20B PRR20C PRR20D PRR20E RBBP8NL RBPMS SMG9 SORBS3 SPAG8 TFCP2 TFIP11 THAP1 TLE5 TNS2 TOX2 TP53BP2 TRIM23 USP54 VAC14 ZBTB10 ZBTB16 ZIM2 ZNF500 ZNF526 ZNF688 ZNF71 ZRANB1 ZSCAN32	18 interacting genes: CDC42EP4 CLCN2 DDR1 E2F1 E2F2 ECEL1 H2BC21 H2BU1 H4-16 HLA-DQA1 HOXC6 PHF1 PRNP PSMB9 RAC2 SPOP TBP TOP1
Entrez ID		5252	6046
HPRD ID		04195	03326
Ensembl ID		ENSG00000112511	ENSG00000204256
Uniprot IDs		A0A140VJR4 A0A1U9X8A3 O43189	A0A024RCR5 A0A1U9X7A8 P25440 X5CF57
PDB IDs		2E5P 2M0O 4HCZ 5XFN 5XFO 5XFP 6WAT 6WAV	1X0J 2DVQ 2DVR 2DVS 2DVV 2E3K 2G4A 2YDW 2YEK 3AQA 3ONI 4A9E 4A9F 4A9H 4A9I 4A9J 4A9M 4A9N 4A9O 4AKN 4ALG 4ALH 4J1P 4MR5 4MR6 4QEU 4QEV 4QEW 4UYF 4UYG 4UYH 5BT5 5DFB 5DFC 5DFD 5DW1 5EK9 5HEL 5HEM 5HEN 5HFQ 5IBN 5IG6 5N2L 5O38 5O39 5O3A 5O3B 5O3C 5O3D 5O3E 5O3F 5O3G 5O3H 5O3I 5U5S 5U6V 5UEW 5XHE 5XHK 6CUI 6DB0 6DBC 6DDI 6DDJ 6E6J 6FFE 6FFF 6FFG 6I80 6I81 6JKE 6K04 6K05 6MO7 6MO8 6MO9 6MOA 6ONY 6SWO 6SWP 6TQ1 6TQ2 6U61 6U71 6U8H 6ULQ 6ULT 6VIY 6YTM 6Z7F 6Z8P 6ZB0 6ZB1 6ZB2 7JX7
Enriched GO Terms of Interacting Partners?
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