PEX6 and RPS14

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PEX6	RPS14
Description		peroxisomal biogenesis factor 6	ribosomal protein S14
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Photoreceptor Cell Cilium	Nucleoplasm Nucleolus Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding ATP Hydrolysis Activity Protein-containing Complex Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Translation Regulator Activity MRNA 5'-UTR Binding Small Ribosomal Subunit RRNA Binding
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Translocation Protein Stabilization	Ribosomal Small Subunit Assembly Negative Regulation Of Transcription By RNA Polymerase II Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Cytoplasmic Translation Translation Regulation Of Translation Erythrocyte Differentiation Maturation Of SSU-rRNA
Pathways		Peroxisomal protein import Peroxisomal protein import	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4+ carriers ( 25778476) Hematocrit ( 32888494) Red blood cell count ( 32888494)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		9 interacting genes: ATF7IP CERS2 NFKBIE PEX1 PEX26 PEX5 RPL27A RPS14 SMAD3	10 interacting genes: APP CALM1 DUX4 KRR1 PEX6 RBBP6 RLIM SMAD2 TAF9 TMEM33
Entrez ID		5190	6208
HPRD ID		03293	00562
Ensembl ID		ENSG00000124587	ENSG00000164587
Uniprot IDs		A0A024RD09 Q13608	P62263
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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