GHRL and MLNR

Number of citations of the paper that reports this interaction (PubMedID 12606621)
12

Data Source:
HPRD (in vitro)

		GHRL	MLNR
Description		ghrelin and obestatin prepropeptide	motilin receptor
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Axon Secretory Granule Lumen Schaffer Collateral - CA1 Synapse Postsynapse Glutamatergic Synapse	Plasma Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Binding Protein Binding Growth Hormone-releasing Hormone Activity Protein Tyrosine Kinase Activator Activity Ghrelin Receptor Binding	G Protein-coupled Receptor Activity G Protein-coupled Peptide Receptor Activity Hormone Binding
	Biological Process	Gastric Acid Secretion Negative Regulation Of Endothelial Cell Proliferation Glucose Metabolic Process G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Actin Polymerization Or Depolymerization Adult Feeding Behavior Response To Hormone Hormone-mediated Signaling Pathway Dendrite Development Negative Regulation Of Angiogenesis Growth Hormone Secretion Positive Regulation Of Insulin Secretion Regulation Of Response To Food Positive Regulation Of Appetite Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Gastric Emptying Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Growth Rate Negative Regulation Of Locomotion Positive Regulation Of Multicellular Organism Growth Regulation Of Cell Population Proliferation Negative Regulation Of Circadian Sleep/wake Cycle, REM Sleep Negative Regulation Of Apoptotic Process Cortisol Secretion Positive Regulation Of MAPK Cascade Response To Estrogen Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Insulin Secretion Decidualization Negative Regulation Of Inflammatory Response Cartilage Development Positive Regulation Of Corticotropin Secretion Positive Regulation Of Cortisol Secretion Response To Electrical Stimulus Positive Regulation Of Synapse Assembly Regulation Of Transmission Of Nerve Impulse Excitatory Postsynaptic Potential Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation Of Protein Tyrosine Kinase Activity Postsynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Postsynapse Organization Positive Regulation Of Small Intestinal Transit Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of Bone Development Positive Regulation Of Sprouting Angiogenesis Positive Regulation Of Eating Behavior Positive Regulation Of Adipose Tissue Development Positive Regulation Of Gastric Mucosal Blood Circulation Positive Regulation Of Small Intestine Smooth Muscle Contraction Regulation Of Gastric Motility Positive Regulation Of Vascular Endothelial Cell Proliferation	G Protein-coupled Receptor Signaling Pathway
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			Erythromycin Mitemcinal
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) ghrelin levels ( 33852427)
Interacting Genes		11 interacting genes: ACE2 AGRP CNTN4 GHRHR GHSR LEP MLNR NPY SIL1 UBQLN1 UBQLN2	4 interacting genes: GHRHR GHRL GPRASP1 MLN
Entrez ID		51738	2862
HPRD ID		05638	04197
Ensembl ID		ENSG00000157017	ENSG00000102539
Uniprot IDs		Q9UBU3	O43193
PDB IDs		1P7X 6H3E
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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