Description |
3-phosphoinositide dependent protein kinase 1 |
integrin subunit beta 3 |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Celecoxib
- Inositol 1,3,4,5-Tetrakisphosphate
- 7-Hydroxystaurosporine
- Bisindolylmaleimide VIII
- Staurosporine
- Bisindolylmaleimide I
- Dexfosfoserine
- 10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine
- 5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE
- 1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA
- 2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine
- 3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione
- 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE
- Fostamatinib
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Diseases |
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GWAS |
- Hip circumference adjusted for BMI ( 34021172)
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- Body mass index ( 25673413)
- Brain morphology (MOSTest) ( 32665545)
- Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183)
- Eosinophil counts ( 32888494)
- Eosinophil percentage of white cells ( 32888494)
- Height ( 33713608)
- High chromosomal aberration frequency (chromosome type) ( 31586183)
- Hip circumference adjusted for BMI ( 34021172)
- Mean platelet volume ( 27863252)
- Medication use (thyroid preparations) ( 31015401)
- Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
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Interacting Genes |
63 interacting genes:
AKT1
AKT2
AKT3
AKTIP
APBB3
APP
BLMH
CARD11
CDAN1
CSK
DDIT4
GIT1
HSP90AA1
ILK
IRS1
ITGB3
KATNBL1
LUC7L2
MAPK8
MTOR
PAK1
PEA15
PHAX
PIK3C3
PKD1
PKN1
PKN2
PNO1
POLDIP2
PRKACA
PRKCB
PRKCD
PRKCE
PRKCI
PRKCZ
PRSS23
PRXL2B
PTK2B
PXN
RALGDS
RPS6KA1
RPS6KA3
RPS6KB1
RPS6KB2
SBF1
SGK1
SGK2
SGK3
SLC9A3R2
SMARCB1
SOCS3
SRC
SRPK1
STRAP
TCAP
UBE2I
WDCP
XPO7
XRCC6
YWHAH
YWHAQ
ZC3HC1
ZNF133
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49 interacting genes:
AKT1
ANGPTL3
APP
CAPN1
CD36
CDK1
COL1A2
DAB1
DAB2
DOK1
EPS8
FBLN2
FGA
FGFR1
FGG
FLNA
FLNB
FN1
GRIA2
HRAS
ILK
ITGA2B
ITGA5
ITGAV
ITGB3BP
KDR
MAPK3
NID1
NUMB
P2RY2
P4HB
PDGFRA
PDGFRB
PDK1
PDPK1
PECAM1
PLA2G2A
PLA2G4A
PTK2
PTK2B
PXN
SHC1
SRC
TGM2
THBS1
THY1
TLN1
TNS2
VTN
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Entrez ID |
5170 |
3690 |
HPRD ID |
05556 |
01428 |
Ensembl ID |
ENSG00000140992
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ENSG00000259207
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Uniprot IDs |
O15530
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P05106
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PDB IDs |
1H1W
1OKY
1OKZ
1UU3
1UU7
1UU8
1UU9
1UVR
1W1D
1W1G
1W1H
1Z5M
2BIY
2PE0
2PE1
2PE2
2R7B
2VKI
2XCH
2XCK
3H9O
3HRC
3HRF
3ION
3IOP
3NAX
3NAY
3NUN
3NUS
3NUU
3NUY
3ORX
3ORZ
3OTU
3PWY
3QC4
3QCQ
3QCS
3QCX
3QCY
3QD0
3QD3
3QD4
3RCJ
3RWP
3RWQ
3SC1
4A06
4A07
4AW0
4AW1
4CT1
4CT2
4RQK
4RQV
4RRV
4XX9
5ACK
5HKM
5HNG
5HO7
5HO8
5LVL
5LVM
5LVN
5LVO
5LVP
5MRD
6WJQ
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1JV2
1KUP
1KUZ
1L5G
1M1X
1M8O
1MIZ
1MK7
1MK9
1RN0
1S4X
1TYE
1U8C
2INI
2K9J
2KNC
2KV9
2L1C
2L91
2LJD
2LJE
2LJF
2MTP
2N9Y
2Q6W
2RMZ
2RN0
2VC2
2VDK
2VDL
2VDM
2VDN
2VDO
2VDP
2VDQ
2VDR
3FCS
3FCU
3IJE
3NID
3NIF
3NIG
3T3M
3T3P
3ZDX
3ZDY
3ZDZ
3ZE0
3ZE1
3ZE2
4CAK
4G1E
4G1M
4MMX
4MMY
4MMZ
4O02
4Z7N
4Z7O
4Z7Q
5HDB
6AVQ
6AVR
6AVU
6BXB
6BXF
6BXJ
6CKB
6MK0
6MSL
6MSU
6NAJ
6V4P
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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