Description |
3-phosphoinositide dependent protein kinase 1 |
AKT serine/threonine kinase 2 |
Image |
|
|
GO Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
- Celecoxib
- Inositol 1,3,4,5-Tetrakisphosphate
- 7-Hydroxystaurosporine
- Bisindolylmaleimide VIII
- Staurosporine
- Bisindolylmaleimide I
- Dexfosfoserine
- 10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine
- 5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE
- 1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA
- 2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine
- 3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione
- 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE
- Fostamatinib
|
|
Diseases |
|
|
GWAS |
- Hip circumference adjusted for BMI ( 34021172)
|
|
Interacting Genes |
63 interacting genes:
AKT1
AKT2
AKT3
AKTIP
APBB3
APP
BLMH
CARD11
CDAN1
CSK
DDIT4
GIT1
HSP90AA1
ILK
IRS1
ITGB3
KATNBL1
LUC7L2
MAPK8
MTOR
PAK1
PEA15
PHAX
PIK3C3
PKD1
PKN1
PKN2
PNO1
POLDIP2
PRKACA
PRKCB
PRKCD
PRKCE
PRKCI
PRKCZ
PRSS23
PRXL2B
PTK2B
PXN
RALGDS
RPS6KA1
RPS6KA3
RPS6KB1
RPS6KB2
SBF1
SGK1
SGK2
SGK3
SLC9A3R2
SMARCB1
SOCS3
SRC
SRPK1
STRAP
TCAP
UBE2I
WDCP
XPO7
XRCC6
YWHAH
YWHAQ
ZC3HC1
ZNF133
|
44 interacting genes:
ABCG8
AKT1
AKT1S1
APOA1
APOB
APP
APPL1
BLVRA
CCL14
CDKN1A
CHUK
CLIP3
ESR1
FOXO4
FSHR
GSK3B
H3C1
HSP90AA1
MEOX2
MTCP1
NAMPT
PDPK1
PICK1
PIP5K1C
PLEKHO1
PNPLA3
POFUT1
POLR1B
PRKDC
RAB3D
REL
SH3RF1
SLC2A4
SNX27
SORBS2
SORBS3
SPRR2A
STEAP4
TCL1A
TCL1B
TMED2
TRIB3
TSC2
XIAP
|
Entrez ID |
5170 |
208 |
HPRD ID |
05556 |
01262 |
Ensembl ID |
ENSG00000140992
|
ENSG00000105221
|
Uniprot IDs |
O15530
|
B4DG79
P31751
|
PDB IDs |
1H1W
1OKY
1OKZ
1UU3
1UU7
1UU8
1UU9
1UVR
1W1D
1W1G
1W1H
1Z5M
2BIY
2PE0
2PE1
2PE2
2R7B
2VKI
2XCH
2XCK
3H9O
3HRC
3HRF
3ION
3IOP
3NAX
3NAY
3NUN
3NUS
3NUU
3NUY
3ORX
3ORZ
3OTU
3PWY
3QC4
3QCQ
3QCS
3QCX
3QCY
3QD0
3QD3
3QD4
3RCJ
3RWP
3RWQ
3SC1
4A06
4A07
4AW0
4AW1
4CT1
4CT2
4RQK
4RQV
4RRV
4XX9
5ACK
5HKM
5HNG
5HO7
5HO8
5LVL
5LVM
5LVN
5LVO
5LVP
5MRD
6WJQ
|
1GZK
1GZN
1GZO
1MRV
1MRY
1O6K
1O6L
1P6S
2JDO
2JDR
2UW9
2X39
2XH5
3D0E
3E87
3E88
3E8D
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|