GET4 and EEF1G

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GET4	EEF1G
Description		guided entry of tail-anchored proteins factor 4	eukaryotic translation elongation factor 1 gamma
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GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol BAT3 Complex	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding Chaperone Binding	Translation Elongation Factor Activity Protein Binding Cadherin Binding
	Biological Process	Protein Insertion Into ER Membrane Cytoplasmic Sequestering Of Protein Tail-anchored Membrane Protein Insertion Into ER Membrane Maintenance Of Unfolded Protein Involved In ERAD Pathway	Translational Elongation Glutathione Metabolic Process Response To Virus
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Eukaryotic Translation Elongation Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		PR interval ( 32439900)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		30 interacting genes: AKT1 ATP5PD BAG6 C1orf109 CAPNS1 CDKN1A CEP126 DNAAF5 DUSP21 EEF1G ENKD1 FBN1 FLYWCH2 GET3 GIT2 KAT5 KIFC2 KRTAP9-3 NUP85 PLK1 PRKAB2 PRKCSH PTMS SDCBP SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2	97 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DLG4 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B ENOX1 FADS1 FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MBD1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 OGT PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24
Entrez ID		51608	1937
HPRD ID		12909	11745
Ensembl ID		ENSG00000239857	ENSG00000254772
Uniprot IDs		Q7L5D6	P26641 Q53YD7
PDB IDs		6AU8	1PBU 5DQS 5JPO
Enriched GO Terms of Interacting Partners?
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