Description |
platelet derived growth factor receptor alpha |
protein tyrosine phosphatase non-receptor type 11 |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Alcohol consumption (max-drinks) ( 29460428)
- Alcohol dependence symptom count ( 29460428)
- Apolipoprotein A1 levels ( 32203549)
- Blood pressure ( 21572416)
- Body mass index ( 26426971)
- Diastolic blood pressure ( 26390057)
- Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
- Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
- Glycated hemoglobin levels ( 34059833)
- HDL cholesterol levels ( 32203549)
- Hematological parameters ( 19820697)
- Hip circumference adjusted for BMI ( 34021172)
- Hypothyroidism ( 22493691)
- Low HDL-cholesterol levels ( 31006500)
- Mean arterial pressure ( 27618448)
- Medication use (agents acting on the renin-angiotensin system) ( 31015401)
- Medication use (beta blocking agents) ( 31015401)
- Medication use (diuretics) ( 31015401)
- Medication use (thyroid preparations) ( 31015401)
- Multiple sclerosis ( 31604244)
- Peripheral artery disease ( 31285632)
- Platelet count ( 22139419 32888494)
- Reaction time ( 29844566)
- Response to alcohol consumption (flushing response) ( 29460428)
- Retinal vascular caliber ( 21060863)
- Rheumatoid arthritis ( 30423114 24390342)
- Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655)
- Systolic blood pressure ( 26390057 30578418)
- Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
- Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
- Tetralogy of Fallot ( 23297363)
- Type 1 diabetes ( 17554300)
- Urate levels ( 23263486)
- Waist-to-hip ratio adjusted for BMI ( 34054925)
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Interacting Genes |
68 interacting genes:
AKT1
ALB
ARNT
AURKA
BECN1
CAV1
CAV3
CBL
CCND2
CD244
CD44
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
CRK
CRKL
EGFR
EPHA2
ERBB2
ERBB3
FBXO25
FGFR4
FZR1
GRB14
GRM1
HGF
ITGAV
ITGB3
JAK1
KASH5
KDELR2
LATS2
MAP2K5
MYC
NF2
PDGFA
PDGFB
PDGFC
PDGFRB
PIK3CA
PIK3R1
PLCG1
PLPP6
PRMT5
PTPN11
RAF1
RAPGEF1
SHB
SHF
SLC9A3R1
SMURF1
SNX2
SNX4
SNX6
SPOCK1
SRPK1
STAT1
STAT3
STAT5A
STAT5B
STK11
TERT
TGFBR2
TP53
TTYH2
ULBP2
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173 interacting genes:
AATK
ACTN4
AKT1
AR
ARHGAP1
AXL
BCR
BDKRB2
BEX1
BEX2
BLZF1
BRAP
BTLA
CALR
CAT
CAV1
CBL
CCKBR
CD33
CDH5
CEACAM1
CHUK
CRKL
CSF2RB
CSF3R
CTDSP1
CTLA4
CXCR4
DAB1
DDR1
DMRTC1
EGFR
EPHA1
EPHA2
EPOR
ERBB2
ERBB3
ERBB4
FAM71E1
FBXW7
FCGR1B
FCGR2B
FCRL3
FGFR2
FGFR4
FLT1
FLT3
FLT4
FRS2
FRS3
FYN
GAB1
GAB2
GAB3
GHR
GMNN
GOLGA2
GRB2
GRIN2B
GTF2A2
HIP1R
HNRNPU
HSP90B1
HSPA5
HSPA9
HSPD1
IFNAR1
IFNGR1
IGF1R
IL4R
IL6ST
ILK
INPP5D
INSR
IRS1
IRS2
IRS4
JAK1
JAK2
KDR
KIR2DL5A
KIT
KLRC1
LAIR1
LCK
LEPR
LIFR
LILRB4
LINC01558
LINC02907
LNX1
LRP1
MAP3K4
MAP3K5
MAPK3
MAPT
MET
MPIG6B
MPL
MPZL1
MS4A2
MVK
MVP
NCOR2
NEB
NEDD9
NOX4
NRG3
NSUN5
NSUN5P2
NTRK1
NTRK2
ORMDL3
P2RX7
PAG1
PDGFRA
PDGFRB
PECAM1
PIK3CA
PIK3CG
PIK3R1
PILRA
PILRB
PLCG1
PNCK
POU2AF1
PRKCA
PRKCB
PRKCH
PRLR
PTK2
PTK2B
PTK7
PTPN6
PXN
RANGRF
RCOR3
RET
ROR2
ROS1
RPIA
SELE
SERF2
SERPINF1
SHC1
SIGLEC11
SIGLEC12
SIGLEC7
SIRPA
SIT1
SLAMF1
SLAMF6
SLC38A1
SLN
SOCS3
SOS1
SPRY2
SRC
SRSF10
STAT1
STAT3
STAT5A
STAT5B
SYNCRIP
TEK
TIE1
TLK1
TNFRSF1A
TREML1
TRIM32
TRMT2B
TSC2
TXNIP
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Entrez ID |
5156 |
5781 |
HPRD ID |
01429 |
01470 |
Ensembl ID |
ENSG00000134853
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ENSG00000179295
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Uniprot IDs |
P16234
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Q06124
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PDB IDs |
1GQ5
5GRN
5K5X
6A32
6JOI
6JOJ
6JOK
6JOL
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2SHP
3B7O
3MOW
3O5X
3TKZ
3TL0
3ZM0
3ZM1
3ZM2
3ZM3
4DGP
4DGX
4GWF
4H1O
4H34
4JE4
4JEG
4JMG
4NWF
4NWG
4OHD
4OHE
4OHH
4OHI
4OHL
4PVG
4QSY
4RDD
5BK8
5DF6
5EHP
5EHR
5I6V
5IBM
5IBS
5X7B
5X94
5XZR
6ATD
6BMR
6BMU
6BMV
6BMW
6BMX
6BMY
6BN5
6CMP
6CMQ
6CMR
6CMS
6CRF
6CRG
6IHZ
6MD7
6MD9
6MDA
6MDB
6MDC
6MDD
6R5G
7JVM
7JVN
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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