NCKIPSD and LGALS4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NCKIPSD	LGALS4
Description		NCK interacting protein with SH3 domain	galectin 4
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GO Annotations	Cellular Component	Cytosol Intermediate Filament	Cytosol Plasma Membrane Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Myosin Binding SH3 Domain Binding Arp2/3 Complex Binding	Protein Binding Carbohydrate Binding
	Biological Process	Endocytosis Cytoskeleton Organization Positive Regulation Of Neuron Projection Development	Cell Adhesion
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Blood protein levels ( 28240269) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Myocardial infarction ( 33532862) Parkinson's disease ( 28892059) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)	Blood protein levels ( 30072576) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		42 interacting genes: ABI2 ARHGEF7 BAIAP2 CCDC187 CPNE2 CYSLTR2 DIAPH2 DIAPH3 DLG4 DMRTB1 ENKD1 FASLG GAS7 GRB2 HSPB1 ITGB1 KHDRBS1 LGALS4 MAPK3 MED25 NCK1 NCK2 PIN1 PKP2 POLR3C PRPF31 PSMD9 PSORS1C2 RBM22 RBP7 RXFP3 SHANK3 SNRPC SORBS3 STAC TSEN54 VEZF1 WAS WASL YWHAG ZBTB47 ZC2HC1C	16 interacting genes: ARPC3 BANP CEP55 EYA2 GOLGA6L9 HOMEZ HOXA1 HSF2BP KIAA1549 KRTAP11-1 MLH1 NCKIPSD RFX6 RRAS2 TENM4 TOX2
Entrez ID		51517	3960
HPRD ID		09450	03949
Ensembl ID		ENSG00000213672	ENSG00000171747
Uniprot IDs		Q9NZQ3	P56470 Q6FHZ4
PDB IDs		6DEC 6DED 6DEE	1X50 4XZP 4YLZ 4YM0 4YM1 4YM2 4YM3 5CBL 5DUU 5DUV 5DUW 5DUX
Enriched GO Terms of Interacting Partners?
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