UBE2J1 and LYVE1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UBE2J1	LYVE1
Description		ubiquitin conjugating enzyme E2 J1	lymphatic vessel endothelial hyaluronan receptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Transmembrane Signaling Receptor Activity Protein Binding Hyaluronic Acid Binding Signaling Receptor Activity
	Biological Process	Protein Polyubiquitination Spermatid Development Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Glycosaminoglycan Catabolic Process Cell-matrix Adhesion Response To Wounding Anatomical Structure Morphogenesis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Hyaluronan uptake and degradation
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		47 interacting genes: AQP2 BIRC2 BRCA1 CD79A CDS1 CLTRN CREB3 CYB561 DIO2 EBP ELOVL4 FAM209A FAM210B FCER1G GKN1 GOLT1A JAGN1 LAPTM5 LRSAM1 LY6G6C LYVE1 MAPKAPK2 MFSD14B MFSD3 MS4A6E PJA2 PLPPR2 PRKN PROKR2 REEP4 RNF2 SEC11C SLC10A6 SLC26A5 TLCD4 TM4SF18 TM4SF19 TMEM14B TMEM31 TMEM51 TMX2 TOPORS TRHR TRIM27 TRIM63 UBA1 UBC	26 interacting genes: AIG1 AQP10 CLCN7 CYSRT1 EMP3 KRT34 KRTAP10-3 KRTAP10-8 KRTAP12-3 KRTAP6-2 KRTAP9-2 NBPF19 NINJ2 NOTCH2NLA NRSN1 PDGFB PIGF SERP2 SLC30A2 SLC38A7 SLC41A2 THSD7A THSD7B UBE2J1 VEGFA YIPF6
Entrez ID		51465	10894
HPRD ID		15599	05753
Ensembl ID		ENSG00000198833	ENSG00000133800
Uniprot IDs		Q9Y385	B2R672 Q9Y5Y7
PDB IDs
Enriched GO Terms of Interacting Partners?
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