REV1 and REV3L

Number of citations of the paper that reports this interaction (PubMedID 15189446)
103

Data Source:
HPRD (two hybrid)

		REV1	REV3L
Description		REV1 DNA directed polymerase	REV3 like, DNA directed polymerase zeta catalytic subunit
Image
GO Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Nucleolus Zeta DNA Polymerase Complex
	Molecular Function	Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Deoxycytidyl Transferase Activity Metal Ion Binding	Nucleotide Binding DNA Binding DNA-directed DNA Polymerase Activity Protein Binding 3'-5' Exonuclease Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	DNA Replication Response To UV Error-prone Translesion Synthesis Error-free Translesion Synthesis	Double-strand Break Repair Via Homologous Recombination DNA-dependent DNA Replication Error-prone Translesion Synthesis
Pathways		Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis	Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	HDL cholesterol levels ( 32203549) Inflammatory bowel disease ( 28067908 23128233) Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 26414677) Psoriasis ( 25574825) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Smoking initiation ( 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 32203549) Ulcerative colitis ( 28067908)
Interacting Genes		14 interacting genes: CLK1 FAAP20 FHL2 GPR45 MAD2L2 POLD3 POLDIP2 POLH POLI POLK POLL REV3L TSC22D2 UBC	6 interacting genes: CHEK2 HDAC2 HDAC4 MAD2L1 MAD2L2 REV1
Entrez ID		51455	5980
HPRD ID		16202	04145
Ensembl ID		ENSG00000135945	ENSG00000009413
Uniprot IDs		Q49AI5 Q9UBZ9	O60673 Q9UG47
PDB IDs		2EBW 2LSI 2LSK 2LSY 2N1G 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5 5VZM 6ASR 6AXD 6WS0 6WS5	3ABD 3ABE 3VU7 4EXT 4GK0 4GK5 5O8K 6BC8 6BCD 6BI7 6EKM 6KEA 6WS0 6WS5
Enriched GO Terms of Interacting Partners?
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