REV1 and GPR45

		REV1	GPR45
Description		REV1 DNA directed polymerase	G protein-coupled receptor 45
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Deoxycytidyl Transferase Activity Metal Ion Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	DNA Replication Response To UV Error-prone Translesion Synthesis Error-free Translesion Synthesis	G Protein-coupled Receptor Signaling Pathway
Pathways		Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Body mass index ( 26426971) Menarche (age at onset) ( 27182965 25231870)
Interacting Genes		14 interacting genes: CLK1 FAAP20 FHL2 GPR45 MAD2L2 POLD3 POLDIP2 POLH POLI POLK POLL REV3L TSC22D2 UBC	4 interacting genes: OTX2 PLEKHB2 REV1 SULT1C4
Entrez ID		51455	11250
HPRD ID		16202	05325
Ensembl ID		ENSG00000135945	ENSG00000135973
Uniprot IDs		Q49AI5 Q9UBZ9	B5B0C1 Q9Y5Y3
PDB IDs		2EBW 2LSI 2LSK 2LSY 2N1G 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5 5VZM 6ASR 6AXD 6WS0 6WS5
Enriched GO Terms of Interacting Partners?
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