UBR5 and CIP2A

Number of citations of the paper that reports this interaction (PubMedID 34145035)
0

Data Source:
BioGRID (two hybrid)

		UBR5	CIP2A
Description		ubiquitin protein ligase E3 component n-recognin 5	cellular inhibitor of PP2A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Ubiquitin-ubiquitin Ligase Activity Ubiquitin Binding Ubiquitin Protein Ligase Activity	Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Protein Polyubiquitination DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Gene Expression Positive Regulation Of Protein Import Into Nucleus Progesterone Receptor Signaling Pathway Protein K48-linked Ubiquitination Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Histone H2A K63-linked Ubiquitination Regulation Of Double-strand Break Repair Negative Regulation Of Double-strand Break Repair
Pathways
Drugs
Diseases
GWAS		Chromosomal aberration frequency (total) ( 31586183) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Rate of cognitive decline in mild cognitive impairment (time interaction) ( 22833209) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		32 interacting genes: BARD1 CIB1 CIP2A CSPP1 DYRK2 ERG GSK3B KPNA1 KPNA2 KPNB1 MAPK1 MOAP1 MYC NR1I2 OTUD5 PAIP1 PAIP2 PCK1 PGR SATB1 SMAD2 SOX2 TCEA1 TOPBP1 TXNIP UBC UBE2A UBE2B UBE2D2 UBE2D3 UBE2L3 ZNF207	11 interacting genes: ATIC CSNK2B GOLGA4 LAMB2 MYC PIK3R1 STUB1 SYNCRIP TOPBP1 UBR5 WWC3
Entrez ID		51366	57650
HPRD ID		06436	11151
Ensembl ID		ENSG00000104517	ENSG00000163507
Uniprot IDs		O95071	Q8TCG1
PDB IDs		1I2T 2QHO 3PT3	5UFL
Enriched GO Terms of Interacting Partners?
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