CDK17 and PRKACG

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		CDK17	PRKACG
Description		cyclin dependent kinase 17	protein kinase cAMP-activated catalytic subunit gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytosol Ciliary Base
	Molecular Function	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Protein Serine/threonine Kinase Activity AMP-activated Protein Kinase Activity CAMP-dependent Protein Kinase Activity Protein Binding ATP Binding Protein Kinase A Regulatory Subunit Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Regulation Of Cell Cycle	Renal Water Homeostasis Protein Phosphorylation Spermatogenesis Male Gonad Development Protein Kinase A Signaling High-density Lipoprotein Particle Assembly
Pathways			PKA-mediated phosphorylation of CREB PKA-mediated phosphorylation of key metabolic factors Triglyceride catabolism PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Regulation of insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins VEGFA-VEGFR2 Pathway CREB1 phosphorylation through the activation of Adenylate Cyclase CREB1 phosphorylation through the activation of Adenylate Cyclase Degradation of GLI1 by the proteasome Degradation of GLI2 by the proteasome GLI3 is processed to GLI3R by the proteasome Hedgehog 'off' state CD209 (DC-SIGN) signaling MAPK6/MAPK4 signaling RET signaling HDL assembly ROBO receptors bind AKAP5 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production
Drugs		Fostamatinib
Diseases
GWAS		Diastolic blood pressure ( 30224653) Manganese levels ( 26025379) Phospholipid levels (plasma) ( 22359512)	Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		13 interacting genes: APAF1 APP BICDL2 CDKN2B DPY30 EPHA2 PRKACG TDRD7 TGFBR1 UBC YWHAG YWHAQ YWHAZ	5 interacting genes: CDK17 CETP HMGN1 TNP1 TNP2
Entrez ID		5128	5568
HPRD ID		09141	01483
Ensembl ID		ENSG00000059758	ENSG00000165059
Uniprot IDs		A0A024RBH0 Q00537	P22612
PDB IDs
Enriched GO Terms of Interacting Partners?
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