UBAP1 and ITGA5

Number of citations of the paper that reports this interaction (PubMedID 26456826)
15

Data Source:
BioGRID (pull down)

		UBAP1	ITGA5
Description		ubiquitin associated protein 1	integrin subunit alpha 5
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GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Cytosol Plasma Membrane Endosome Membrane Intracellular Membrane-bounded Organelle	Ruffle Plasma Membrane Cell-cell Junction Focal Adhesion Integrin Complex Cell Surface Ruffle Membrane Integrin Alpha5-beta1 Complex Alphav-beta3 Integrin-vitronectin Complex
	Molecular Function	Protein Binding Ubiquitin Binding	Virus Receptor Activity Platelet-derived Growth Factor Receptor Binding Protein Binding Vascular Endothelial Growth Factor Receptor 2 Binding Metal Ion Binding
	Biological Process	Protein Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway	Angiogenesis Cell Adhesion Integrin-mediated Signaling Pathway CD40 Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-substrate Adhesion Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Wound Healing, Spreading Of Epidermal Cells Endodermal Cell Differentiation Viral Entry Into Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Sprouting Angiogenesis Negative Regulation Of Anoikis
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Elastic fibre formation Fibronectin matrix formation Cell surface interactions at the vascular wall Integrin cell surface interactions Integrin cell surface interactions Signal transduction by L1 RUNX2 regulates genes involved in cell migration
Drugs			Resveratrol
Diseases
GWAS		Creatine kinase levels ( 29403010) Fruit consumption ( 32066663) Pulse pressure ( 30224653)	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: ITGA5 MAP3K1 PPIC PTPN23 UBC	33 interacting genes: ANGPT1 ANGPT2 ANGPTL3 ARHGAP5 AUP1 CD9 CHMP2A CLK1 COL18A1 COL1A1 EGFR ERBB2 FGFR2 FLT4 FN1 GIPC1 GPR182 GRK6 ITGB1 ITGB3 ITGB5 L1CAM LGALS3BP NISCH PECAM1 RABIF SHARPIN SPP1 STAMBP THAP1 TNC UBAP1 VCL
Entrez ID		51271	3678
HPRD ID		15597	00627
Ensembl ID		ENSG00000165006	ENSG00000161638
Uniprot IDs		A0A6G6AA68 Q9NZ09	B2R627 P08648
PDB IDs		1WGN 4AE4 5LM1	3VI3 3VI4 4WJK 4WK0 4WK2 4WK4
Enriched GO Terms of Interacting Partners?
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