ITGA5 and RABIF

Number of citations of the paper that reports this interaction (PubMedID 10094488)
15

Data Source:
BioGRID (two hybrid)

		ITGA5	RABIF
Description		integrin subunit alpha 5	RAB interacting factor
Image
GO Annotations	Cellular Component	Ruffle Plasma Membrane Cell-cell Junction Focal Adhesion Integrin Complex Cell Surface Ruffle Membrane Integrin Alpha5-beta1 Complex Alphav-beta3 Integrin-vitronectin Complex	Cytosol Membrane
	Molecular Function	Virus Receptor Activity Platelet-derived Growth Factor Receptor Binding Protein Binding Vascular Endothelial Growth Factor Receptor 2 Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding
	Biological Process	Angiogenesis Cell Adhesion Integrin-mediated Signaling Pathway CD40 Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-substrate Adhesion Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Wound Healing, Spreading Of Epidermal Cells Endodermal Cell Differentiation Viral Entry Into Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Sprouting Angiogenesis Negative Regulation Of Anoikis	Post-Golgi Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Catalytic Activity Membrane Fusion
Pathways		Elastic fibre formation Fibronectin matrix formation Cell surface interactions at the vascular wall Integrin cell surface interactions Integrin cell surface interactions Signal transduction by L1 RUNX2 regulates genes involved in cell migration
Drugs		Resveratrol
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		33 interacting genes: ANGPT1 ANGPT2 ANGPTL3 ARHGAP5 AUP1 CD9 CHMP2A CLK1 COL18A1 COL1A1 EGFR ERBB2 FGFR2 FLT4 FN1 GIPC1 GPR182 GRK6 ITGB1 ITGB3 ITGB5 L1CAM LGALS3BP NISCH PECAM1 RABIF SHARPIN SPP1 STAMBP THAP1 TNC UBAP1 VCL	29 interacting genes: EIF3F ITGA2 ITGA3 ITGA5 ITGA6 KIFC3 KYAT3 LAMTOR5 LARP1B LMCD1 LNX1 LRMDA LZTS1 RAB10 RAB15 RAB19 RAB1A RAB1B RAB3A RAB3B RAB3C RAB3D RAB8A RASSF5 REL TCF4 TERF2IP UTP14A ZNF544
Entrez ID		3678	5877
HPRD ID		00627	04566
Ensembl ID		ENSG00000161638	ENSG00000183155
Uniprot IDs		B2R627 P08648	P47224 Q53EV1
PDB IDs		3VI3 3VI4 4WJK 4WK0 4WK2 4WK4	1FWQ 2FU5
Enriched GO Terms of Interacting Partners?
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