TRIM17 and LRSAM1

Number of citations of the paper that reports this interaction (PubMedID 22493164)
7

Data Source:
BioGRID (two hybrid)

		TRIM17	LRSAM1
Description		tripartite motif containing 17	leucine rich repeat and sterile alpha motif containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm	Cytoplasm Cytosol Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein-macromolecule Adaptor Activity Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Autophagy Regulation Of Gene Expression Protein Ubiquitination Regulation Of Protein Localization Innate Immune Response Protein Autoubiquitination	Protein Polyubiquitination Autophagy Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis Positive Regulation Of Xenophagy Positive Regulation Of Autophagosome Assembly
Pathways		Interferon gamma signaling	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy ( 30066433)	Mean corpuscular volume ( 32888494)
Interacting Genes		19 interacting genes: HGS LGALS3 LGALS8 LRSAM1 MEOX2 MNAT1 TRAF6 TRIM39 TRIM41 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2N UBE2W USP15	45 interacting genes: ATXN1 ATXN7 C5 CCDC6 DMAP1 FAM178B FXR1 GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MAGEA1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSC1 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2I UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11 XAF1 ZMAT4
Entrez ID		51127	90678
HPRD ID		05839	14325
Ensembl ID		ENSG00000162931	ENSG00000148356
Uniprot IDs		A0A024R3R3 B3KP04 Q9Y577	A0A024R870 Q6UWE0
PDB IDs
Enriched GO Terms of Interacting Partners?
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