NTM and CCKBR

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		NTM	CCKBR
Description		neurotrimin	cholecystokinin B receptor
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Cholecystokinin Receptor Activity Protein Binding Gastrin Receptor Activity Peptide Hormone Binding Type B Gastrin/cholecystokinin Receptor Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Cell Adhesion Neuron Recognition	Gastric Acid Secretion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Cell Population Proliferation Cholecystokinin Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity PH Reduction Digestive Tract Development Gland Development
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Peptide ligand-binding receptors G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK
Drugs			Pentagastrin Cholecystokinin
Diseases
GWAS		Adult body size ( 32376654) Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Alzheimer's disease ( 33654092) Asperger disorder ( 21182207) Blood protein levels ( 30072576) Body size at age 10 ( 32376654) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Familial lung adenocarcinoma ( 29924316) Feeling worry ( 29500382) Food addiction ( 27106561) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Glucocorticoid-induced osteonecrosis (time dependent analysis) ( 26265699) Gut microbiota (functional units) ( 27694959) Intake of total sugars ( 31005972) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Male fertility ( 22633400) Mental health study participation (completed survey) ( 31263887) Myopia ( 27182965) Obesity-related traits ( 23251661) Plasma anti-thyroglobulin levels ( 29678681) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592) Severe exacerbations in childhood asthma ( 33093117) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Sunburns ( 23548203)	Diastolic blood pressure ( 30224653) Early spontaneous preterm birth ( 31194736) Gastroesophageal reflux disease ( 31527586) Malaria ( 31844061) Rheumatic heart disease ( 34106200)
Interacting Genes		20 interacting genes: APP C19orf47 CCKBR EFEMP2 KRTAP1-1 KRTAP3-2 KRTAP5-9 KRTAP9-3 LHB LINGO1 LSAMP MRPL12 NBPF19 NEGR1 NOTCH2NLA P4HB PAX4 QRFPR SPRY1 VWC2	10 interacting genes: ADRB2 ATP13A2 CCK CCKAR CCR4 DRD2 NTM PPP1R9B PTPN11 SLCO1B3
Entrez ID		50863	887
HPRD ID		06398	00323
Ensembl ID		ENSG00000182667	ENSG00000110148
Uniprot IDs		B7Z1I4 Q9P121	E9PIC8 P32239
PDB IDs		6DLF	1L4T
Enriched GO Terms of Interacting Partners?
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