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CCKBR

Description cholecystokinin B receptor
Image
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Membrane
Molecular Function
  • G Protein-coupled Receptor Activity
  • Cholecystokinin Receptor Activity
  • Protein Binding
  • Gastrin Receptor Activity
  • Peptide Hormone Binding
  • Type B Gastrin/cholecystokinin Receptor Binding
  • 1-phosphatidylinositol-3-kinase Regulator Activity
Biological Process
  • Gastric Acid Secretion
  • Cell Surface Receptor Signaling Pathway
  • G Protein-coupled Receptor Signaling Pathway
  • Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
  • Positive Regulation Of Cytosolic Calcium Ion Concentration
  • Positive Regulation Of Cell Population Proliferation
  • Cholecystokinin Signaling Pathway
  • Regulation Of Phosphatidylinositol 3-kinase Activity
  • PH Reduction
  • Digestive Tract Development
  • Gland Development
Pathways
  • Peptide ligand-binding receptors
  • G alpha (q) signalling events
  • Gastrin-CREB signalling pathway via PKC and MAPK
Drugs
  • Pentagastrin
  • Cholecystokinin
Diseases
GWAS
  • Diastolic blood pressure ( 30224653)
  • Early spontaneous preterm birth ( 31194736)
  • Gastroesophageal reflux disease ( 31527586)
  • Malaria ( 31844061)
  • Rheumatic heart disease ( 34106200)
Interacting Genes 10 interacting genes: ADRB2 ATP13A2 CCK CCKAR CCR4 DRD2 NTM PPP1R9B PTPN11 SLCO1B3
Entrez ID 887
HPRD ID 00323
Ensembl ID ENSG00000110148
Uniprot IDs E9PIC8 P32239
PDB IDs 1L4T
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025