TAS2R10 and PDCD1LG2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TAS2R10	PDCD1LG2
Description		taste 2 receptor member 10	programmed cell death 1 ligand 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Taste Receptor Activity Bitter Taste Receptor Activity	Molecular_function Protein Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste G Protein-coupled Receptor Signaling Pathway	Adaptive Immune Response Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide
Pathways		G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)	PD-1 signaling
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488 28240269) Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		4 interacting genes: HERPUD2 PDCD1LG2 RTP4 SSMEM1	21 interacting genes: ATP6V0C ERMP1 EXOSC8 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35C2 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97
Entrez ID		50839	80380
HPRD ID		11990	16147
Ensembl ID		ENSG00000121318	ENSG00000197646
Uniprot IDs		Q9NYW0	Q9BQ51
PDB IDs			6UMT
Enriched GO Terms of Interacting Partners?
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