PDCD1LG2 and MFSD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PDCD1LG2	MFSD6
Description		programmed cell death 1 ligand 2	major facilitator superfamily domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Integral Component Of Membrane	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Adaptive Immune Response Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Pathways		PD-1 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Serum alkaline phosphatase levels ( 33339817)	Arthritis (juvenile idiopathic) ( 33106285) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 31015462) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494)
Interacting Genes		21 interacting genes: ATP6V0C ERMP1 EXOSC8 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35C2 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97	43 interacting genes: ADIPOQ ALG8 ANKAR APH1A APOL3 AQP7 C19orf18 C2orf88 CD79A CYB5R3 EBP ERGIC3 GJA8 GJB2 GPR152 GPR42 GPX8 HIBCH LY6E MFSD4B MSTN NKG7 OSGEPL1 PDCD1LG2 SELENOK SGPL1 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC39A2 SMIM1 SSMEM1 STAT1 STX12 SYNDIG1 TMEM179B TMEM237 TMEM242 TMEM258 TSPO2 WDR75
Entrez ID		80380	54842
HPRD ID		16147	13369
Ensembl ID		ENSG00000197646	ENSG00000151690
Uniprot IDs		Q9BQ51	Q6ZSS7
PDB IDs		6UMT
Enriched GO Terms of Interacting Partners?
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