PAX6 and STAC

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

PAX6

STAC

Description paired box 6 SH3 and cysteine rich domain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Body mass index ( 22344219 28892062)
  • Depression ( 29700475)
  • Diastolic blood pressure ( 27841878)
  • Feeling worry ( 29500382)
  • General factor of neuroticism ( 30867560)
  • Irritable mood ( 29500382)
  • Major depressive disorder ( 27479909)
  • Neurociticism ( 29500382)
  • Optic disc area ( 28073927)
  • Refractive error ( 32231278)
  • Systolic blood pressure ( 27841878)
  • Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325)
  • Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
  • Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
  • Asthma ( 29273806)
  • Brooding (response to stress) ( 30886212)
  • Celiac disease ( 23936387)
  • Erectile dysfunction in type 1 diabetes ( 22704111)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 31537649)
  • Metabolite levels ( 23823483)
  • Smoking behaviour (maximum cigarettes in a 24 hour period) ( 29532581)
Interacting Genes 136 interacting genes: ACOT12 AP1M1 ARIH2 ATP6V0D2 ATP6V1C2 BANP BCL2L15 C1orf109 C2CD6 CCDC103 CCDC6 CCL26 CDK3 CDX2 CGGBP1 CHAF1A CIB3 CINP CKS1B CREBBP CSNK2A1 CSTF3 CTNNA3 CXorf38 DHPS DIAPH1 DLG1 DYNLL1 EAF1 EFHC1 EIF1AD EN1 EP300 ESRRG FAM50B GAS2L2 GCM2 GEMIN2 GPANK1 GRHL2 HGS HIPK2 HIVEP2 HMBOX1 HMGB3 HNRNPC HOMER3 HOXA1 HOXB1 HOXC8 HOXC9 INPP5D IPO13 KANK2 KCTD7 KRTAP9-3 KRTAP9-8 LARP4 LHX2 LNPK LONRF1 LXN LYSMD1 MAFG MAPRE1 MFAP1 MID1 MIPOL1 MISP MITF MORN3 MPPED2 MRPL53 NCDN NFKBID NFYC NGLY1 NKIRAS2 PATJ PBX1 PDE4C PICK1 PIN1 PKNOX1 POLR3C POLR3GL PPIL4 PRKAG1 PROX1 PSORS1C2 QRICH1 RAG1 RANBP3 RAX RB1 RCN1 RGS3 RNF111 SAE1 SEC14L4 SET SHANK3 SIGLEC6 SIX3 SLAMF1 SLC12A8 SMARCA4 SOX10 SOX3 SPDYC SPG21 SRSF11 STAC SUMO1 TBP TCP11L1 THOC1 TLK1 TLK2 TRAPPC6A TRIM11 TRIP10 TRMT112 UBE2F UBE2K UBE3A UBXN2B UBXN7 USHBP1 VCX2 VSX2 WASHC3 WT1 ZBED1 ZNF124 ZNF410 22 interacting genes: APP FBXO25 GOLGA2 KANK2 KIAA1958 LIMD1 LMNA LRRK2 LZTS2 MEOX2 NBPF19 NCKIPSD NEDD4L NOTCH2NLA PAX5 PAX6 PJA1 POU6F2 RNF208 STAT5B TRIP6 TRMO
Entrez ID 5080 6769
HPRD ID 06167 11890
Ensembl ID ENSG00000007372 ENSG00000144681
Uniprot IDs A0A1W2PRA8 D1KF47 F1T0F8 P26367 Q66SS1 B4DR96 B4DZ13 E9PEA7 Q8WUK8 Q99469
PDB IDs 2CUE 6PAX 2DL4 6B25
Enriched GO Terms of Interacting Partners?
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