PAX5 and ACOT12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PAX5	ACOT12
Description		paired box 5	acyl-CoA thioesterase 12
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GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle	Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Acetyl-CoA Hydrolase Activity Protein Binding ATP Binding Lipid Binding Long-chain Fatty Acyl-CoA Binding Identical Protein Binding Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Humoral Immune Response Multicellular Organism Development Spermatogenesis Aging Animal Organ Morphogenesis Lateral Ventricle Development Cerebral Cortex Development Adult Behavior Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Cranial Skeleton Morphogenesis Anatomical Structure Development Negative Regulation Of Histone H3-K9 Methylation	Acetyl-CoA Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process
Pathways		RUNX1 regulates transcription of genes involved in BCR signaling	Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alzheimer's disease ( 30636644) Bipolar disorder ( 33169155) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Coronary artery disease in type 1 diabetes ( 29695241) ghrelin levels ( 33852427) HIV-1 susceptibility ( 25786224) Intelligence ( 22449649) Major depressive disorder ( 27479909) Moderate to vigorous physical activity levels ( 29899525) Morning person ( 30696823) Obesity-related traits ( 22013104)	Bipolar disorder ( 31043756)
Interacting Genes		55 interacting genes: ACOT12 BCAS2 C1orf109 CCL19 CCNC CDK3 CIB3 CKS1B CREBBP CSNK2A1 CXorf38 DAXX DTX2 EBF1 ETS1 FBLN1 GNG13 GRHL2 HGS HMBOX1 HMGB3 HOXC8 ID2 ID3 KLHL38 KPNA1 KPNA2 KRTAP10-8 KRTAP9-3 LARP4 LDLRAP1 LONRF1 MAPK1 MAPK9 MYB NEIL2 NFYC NGLY1 OSGIN1 PNMA5 RAD52 RB1 RNF144B RUNX1 SAE1 SEC14L4 STAC TBP TLE4 TLK2 UBE2I UBE3A UBXN2B UBXN7 ZMYM5	9 interacting genes: ACOT7 MEOX1 MEOX2 NAA10 NAA11 PAX5 PAX6 REL ZBTB8A
Entrez ID		5079	134526
HPRD ID		01334	16680
Ensembl ID		ENSG00000196092	ENSG00000172497
Uniprot IDs		C0KTE5 C0KTF5 E7EQT0 E7ERK2 E7ERW5 E7ES87 Q02548	Q8WYK0
PDB IDs		1K78 1MDM	3B7K 4MOB 4MOC
Enriched GO Terms of Interacting Partners?
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