ACOT12 and ACOT7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ACOT12	ACOT7
Description		acyl-CoA thioesterase 12	acyl-CoA thioesterase 7
Image
GO Annotations	Cellular Component	Cytosol	Nucleoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	Acetyl-CoA Hydrolase Activity Protein Binding ATP Binding Lipid Binding Long-chain Fatty Acyl-CoA Binding Identical Protein Binding Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity	Fatty-acyl-CoA Binding Protein Binding Palmitoyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	Acetyl-CoA Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process	Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process
Pathways		Mitochondrial Fatty Acid Beta-Oxidation	Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Body shape index ( 34021172) HDL cholesterol levels in HIV infection ( 33109212) Metabolite levels ( 31628463) QT interval ( 19305408) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		9 interacting genes: ACOT7 MEOX1 MEOX2 NAA10 NAA11 PAX5 PAX6 REL ZBTB8A	26 interacting genes: ACOT12 ATXN1 ATXN1L BAG4 CAMK2B CDC42 CRYAB DAZAP2 DLC1 ENKD1 FXR1 HOXA1 LMNA MAGEA3 MAGEA6 NCOA5 POT1 POU6F1 SPATC1L TERF1 THAP1 TINF2 UBQLN1 UBQLN2 UBXN1 ZNF438
Entrez ID		134526	11332
HPRD ID		16680	12517
Ensembl ID		ENSG00000172497	ENSG00000097021
Uniprot IDs		Q8WYK0	O00154
PDB IDs		3B7K 4MOB 4MOC	2QQ2
Enriched GO Terms of Interacting Partners?
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