OTX1 and ADAM12

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

OTX1

ADAM12

Description orthodenticle homeobox 1 ADAM metallopeptidase domain 12
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Fruit consumption ( 32066663)
  • Neurociticism ( 29500382)
  • Regular attendance at a religious group ( 29970889)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Blood protein levels ( 30072576)
  • Endometrial cancer ( 24096698)
  • Extremely high intelligence ( 29731509)
  • Heel bone mineral density ( 30598549)
  • Intraocular pressure ( 30054594)
  • Itch intensity from mosquito bite ( 28199695)
  • Loneliness ( 27629369)
  • Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
  • Mild influenza (H1N1) infection ( 26379185)
  • Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070 27021288)
  • Placental abruption ( 29884306)
  • Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)
  • Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Visceral fat ( 22589738)
Interacting Genes 144 interacting genes: ADAM12 ADAMTSL4 ALPP ANKRD10 ARHGEF17 ARID5A ATG9B BHLHB9 C10orf55 C11orf1 CCN4 CERCAM CH25H CHIC2 CHRD CHRDL2 COL8A1 COMP CTAG2 CYSRT1 DPY30 EFEMP2 ETFDH FAM168B FAM72B FBLN2 FBLN5 FHL5 GEMIN8P4 GPRIN2 GRN HIVEP1 INTS11 KCNK16 KLHL26 KPRP KRT31 KRT35 KRT37 KRT81 KRT85 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP17-1 KRTAP19-2 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1B LCE1C LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LGALS13 M1AP MDFI MGAT5B MIIP MTNR1B NBPF19 NDUFAF6 NECTIN3 NHLRC4 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLEKHG4 PLSCR2 POU2AF1 PRICKLE4 PRR13 PRR22 RBPMS RGS17 RGS19 RGS20 RNF144B RTN4R SLC15A2 SMARCC1 SPRY1 SPRY2 SPRY4 SPRYD7 TEX37 TLE4 TNS2 TRIM42 TRIP6 TSPAN4 UBAP2 USP54 VWC2 VWC2L WWOX YPEL3 ZBTB42 ZNF330 ZNF34 42 interacting genes: ACTN2 ADAMTSL4 CYSRT1 DOCK1 EGF ESM1 FHL5 FSTL3 GRB2 GUCD1 HOXA1 IGFBP3 IGFBP5 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP12-2 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-6 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-8 LCE5A MAPKBP1 NBPF19 NOTCH2NLA OTX1 PACSIN3 PIK3R1 RECK SH3D19 SLC15A2 SPRY1 SPRY4 SRC TFAP2D TUBGCP2 YES1
Entrez ID 5013 8038
HPRD ID 08964 04092
Ensembl ID ENSG00000115507 ENSG00000148848
Uniprot IDs P32242 A8K6G4 O43184 U5NE98
PDB IDs
Enriched GO Terms of Interacting Partners?
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