ACO2 and CD244

		ACO2	CD244
Description		aconitase 2	CD244 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Aconitate Hydratase Activity Iron Ion Binding Citrate Dehydratase Activity 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	Protein Binding Signaling Receptor Activity MHC Class I Protein Binding
	Biological Process	Liver Development Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle Citrate Metabolic Process Isocitrate Metabolic Process Response To Isolation Stress	Adaptive Immune Response Natural Killer Cell Activation Involved In Immune Response Signal Transduction Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Granzyme B Production
Pathways		Mitochondrial protein import Citric acid cycle (TCA cycle)	Cell surface interactions at the vascular wall
Drugs		Isocitric Acid 4-Hydroxy-Aconitate Ion Alpha-Methylisocitric Acid Aconitate Ion Tricarballylic acid
Diseases
GWAS		Adult body size ( 32376654) Asthma ( 32296059) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Blood protein levels ( 28240269) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		6 interacting genes: APP ATXN1L C5AR2 CD244 CDC42 SUMO4	11 interacting genes: ACO2 ARHGEF7 CD247 CD48 LAT OLFML2B PCGF1 PDGFRA SH2D1A SH2D1B TOMM40L
Entrez ID		50	51744
HPRD ID		00012	16121
Ensembl ID		ENSG00000100412	ENSG00000122223
Uniprot IDs		A0A7I2V586 Q99798	Q9BZW8
PDB IDs
Enriched GO Terms of Interacting Partners?
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