YBX1 and SLC6A4

Number of citations of the paper that reports this interaction (PubMedID 15229244)
20

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		YBX1	SLC6A4
Description		Y-box binding protein 1	solute carrier family 6 member 4
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm U12-type Spliceosomal Complex Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome CRD-mediated MRNA Stability Complex Histone Pre-mRNA 3'end Processing Complex Messenger Ribonucleoprotein Complex Ribonucleoprotein Complex	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Endosome Membrane Endomembrane System Neuron Projection Membrane Raft Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane Serotonergic Synapse
	Molecular Function	Nucleic Acid Binding DNA Binding Chromatin Binding Double-stranded DNA Binding Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding MiRNA Binding GTPase Binding C5-methylcytidine-containing RNA Binding Sequence-specific Double-stranded DNA Binding	Neurotransmitter Transmembrane Transporter Activity Serotonin:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Syntaxin-1 Binding Cocaine Binding Identical Protein Binding Metal Ion Binding Nitric-oxide Synthase Binding Actin Filament Binding Serotonin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing Epidermis Development Regulation Of Gene Expression Negative Regulation Of Translation Positive Regulation Of Transcription By RNA Polymerase II MRNA Stabilization Embryonic Morphogenesis RNA Transport TRNA Transport Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Division CRD-mediated MRNA Stabilization Cellular Response To Interleukin-7 Protein Localization To Cytoplasmic Stress Granule MiRNA Transport Negative Regulation Of Cellular Senescence	Response To Hypoxia Neurotransmitter Transport Response To Nutrient Memory Circadian Rhythm Response To Xenobiotic Stimulus Response To Toxic Substance Positive Regulation Of Gene Expression Positive Regulation Of Serotonin Secretion Monoamine Transport Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Negative Regulation Of Synaptic Transmission, Dopaminergic Response To Estradiol Social Behavior Sodium Ion Transmembrane Transport Neurotransmitter Biosynthetic Process Vasoconstriction Sperm Ejaculation Negative Regulation Of Neuron Differentiation Positive Regulation Of Cell Cycle Negative Regulation Of Organ Growth Brain Morphogenesis Serotonin Uptake Cellular Response To Retinoic Acid Cellular Response To CGMP Regulation Of Thalamus Size
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Noncanonical activation of NOTCH3	Serotonin clearance from the synaptic cleft
Drugs			Fluvoxamine Amphetamine Phentermine Tramadol Citalopram Benzatropine Venlafaxine Atomoxetine Amitriptyline Protriptyline Loxapine Meperidine Imipramine Fluoxetine Duloxetine Dextromethorphan Nortriptyline Amoxapine Fenfluramine Mazindol Trazodone Verapamil Paroxetine Trimipramine Minaprine Pseudoephedrine Cocaine Cyclobenzaprine Dopamine Sertraline Sibutramine Chlorpheniramine Doxepin Nefazodone Desipramine Escitalopram Dexfenfluramine Aripiprazole Clomipramine Ephedra sinica root MMDA Midomafetamine 4-Methoxyamphetamine Metamfetamine Nomifensine Zimelidine Amineptine Bicifadine Milnacipran OPC-14523 CRx-119 Amitifadine Lumateperone Mianserin Tesofensine Tapentadol Vilazodone Desvenlafaxine Dexmethylphenidate Serotonin Levomilnacipran Butriptyline Vortioxetine Dosulepin Nisoxetine Lorpiprazole Zotepine Dasotraline
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Height ( 28552196)
Interacting Genes		122 interacting genes: ACTA2 AKT1 ANKRD2 APBB1 C1QBP CALM1 CASP8 CSNK2A1 CTCF DANCR DUX4 FBXO33 FMR1 FUS GSK3B H1-2 HABP4 HLA-C HNRNPD HNRNPK IL7R IREB2 IRF1 JAM2 LCK LCP2 LSM3 MAPK1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYC MYCN NFYB OGT PCBP2 PCNA PRPF40A PTPRF PURA RBBP6 RPS6KA1 RPS6KA3 SLC6A4 SMAD3 SMU1 SREK1 SRSF9 TFAP2A TP53 TRAF6 VEGFA VPS35	8 interacting genes: A2M CALR CANX GPM6B SMAD2 STX1A VAMP2 YBX1
Entrez ID		4904	6532
HPRD ID		01095	01640
Ensembl ID		ENSG00000065978	ENSG00000108576
Uniprot IDs		P67809	B2R7Y7 P31645
PDB IDs		1H95 5YTS 5YTT 5YTV 5YTX 6A6L 6KTC 6KUG 6LMR 6LMS	5I6X 5I6Z 5I71 5I73 5I74 5I75 6AWN 6AWO 6AWP 6AWQ 6DZV 6DZW 6DZY 6DZZ 6VRH 6VRK 6VRL 6W2B 6W2C
Enriched GO Terms of Interacting Partners?
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