SLC6A4 and GPM6B

Number of citations of the paper that reports this interaction (PubMedID 18581270)
14

Data Source:
BioGRID (pull down)

		SLC6A4	GPM6B
Description		solute carrier family 6 member 4	glycoprotein M6B
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Endosome Membrane Endomembrane System Neuron Projection Membrane Raft Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane Serotonergic Synapse	Plasma Membrane Integral Component Of Membrane Membrane Raft
	Molecular Function	Neurotransmitter Transmembrane Transporter Activity Serotonin:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Syntaxin-1 Binding Cocaine Binding Identical Protein Binding Metal Ion Binding Nitric-oxide Synthase Binding Actin Filament Binding Serotonin Binding	Molecular_function
	Biological Process	Response To Hypoxia Neurotransmitter Transport Response To Nutrient Memory Circadian Rhythm Response To Xenobiotic Stimulus Response To Toxic Substance Positive Regulation Of Gene Expression Positive Regulation Of Serotonin Secretion Monoamine Transport Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Negative Regulation Of Synaptic Transmission, Dopaminergic Response To Estradiol Social Behavior Sodium Ion Transmembrane Transport Neurotransmitter Biosynthetic Process Vasoconstriction Sperm Ejaculation Negative Regulation Of Neuron Differentiation Positive Regulation Of Cell Cycle Negative Regulation Of Organ Growth Brain Morphogenesis Serotonin Uptake Cellular Response To Retinoic Acid Cellular Response To CGMP Regulation Of Thalamus Size	Ossification Nervous System Development Protein Transport Positive Regulation Of Bone Mineralization Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Serotonin Uptake Regulation Of Focal Adhesion Assembly Extracellular Matrix Assembly Negative Regulation Of Protein Localization To Cell Surface
Pathways		Serotonin clearance from the synaptic cleft
Drugs		Fluvoxamine Amphetamine Phentermine Tramadol Citalopram Benzatropine Venlafaxine Atomoxetine Amitriptyline Protriptyline Loxapine Meperidine Imipramine Fluoxetine Duloxetine Dextromethorphan Nortriptyline Amoxapine Fenfluramine Mazindol Trazodone Verapamil Paroxetine Trimipramine Minaprine Pseudoephedrine Cocaine Cyclobenzaprine Dopamine Sertraline Sibutramine Chlorpheniramine Doxepin Nefazodone Desipramine Escitalopram Dexfenfluramine Aripiprazole Clomipramine Ephedra sinica root MMDA Midomafetamine 4-Methoxyamphetamine Metamfetamine Nomifensine Zimelidine Amineptine Bicifadine Milnacipran OPC-14523 CRx-119 Amitifadine Lumateperone Mianserin Tesofensine Tapentadol Vilazodone Desvenlafaxine Dexmethylphenidate Serotonin Levomilnacipran Butriptyline Vortioxetine Dosulepin Nisoxetine Lorpiprazole Zotepine Dasotraline
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Height ( 28552196)	Delayed reward discounting ( 29230059) Glaucoma (primary open-angle) ( 33627673)
Interacting Genes		8 interacting genes: A2M CALR CANX GPM6B SMAD2 STX1A VAMP2 YBX1	7 interacting genes: CLN8 EGFR ERBB2 ERGIC3 MTNR1B SLC6A4 STX1A
Entrez ID		6532	2824
HPRD ID		01640	02082
Ensembl ID		ENSG00000108576	ENSG00000046653
Uniprot IDs		B2R7Y7 P31645	A0A024RBV7 A0A024RBX1 Q13491 Q59FD5
PDB IDs		5I6X 5I6Z 5I71 5I73 5I74 5I75 6AWN 6AWO 6AWP 6AWQ 6DZV 6DZW 6DZY 6DZZ 6VRH 6VRK 6VRL 6W2B 6W2C
Enriched GO Terms of Interacting Partners?
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