NOVA1 and RPP14

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		NOVA1	RPP14
Description		NOVA alternative splicing regulator 1	ribonuclease P/MRP subunit p14
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Intracellular Membrane-bounded Organelle	Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Sequence-specific MRNA Binding	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Cold-induced Thermogenesis	TRNA 5'-leader Removal RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28892062) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophilic esophagitis ( 25407941) Finger osteoarthritis severity (hand Klsum) ( 33055079) Hand grip strength ( 29691431) Metabolite levels ( 23823483) Migraine ( 27182965) Neuritic plaque ( 31497858) Overweight status ( 25133637) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) Zinc levels ( 26025379)	Height ( 28552196) Hemoglobin levels ( 32327693) Mitochondrial heteroplasmy measurement ( 33731350) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)
Interacting Genes		5 interacting genes: APP PCBP1 RPP14 SMARCC2 SRPK1	22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277
Entrez ID		4857	11102
HPRD ID		03693	18001
Ensembl ID		ENSG00000139910	ENSG00000163684
Uniprot IDs		B7Z770 P51513	O95059
PDB IDs		1DT4 2ANN 2ANR	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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