RPP14 and RPP40

Number of citations of the paper that reports this interaction (PubMedID 15096576)
48

Data Source:
HPRD (in vitro)

		RPP14	RPP40
Description		ribonuclease P/MRP subunit p14	ribonuclease P/MRP subunit p40
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Multimeric Ribonuclease P Complex
	Molecular Function	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Ribonuclease MRP Activity Ribonuclease P Activity Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRNA 5'-leader Removal Endonucleolytic Cleavage Involved In TRNA Processing
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Height ( 28552196) Hemoglobin levels ( 32327693) Mitochondrial heteroplasmy measurement ( 33731350) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)
Interacting Genes		22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277	8 interacting genes: MEOX2 POP1 POP7 PTEN RPP14 RPP21 RPP30 RPP38
Entrez ID		11102	10799
HPRD ID		18001	09361
Ensembl ID		ENSG00000163684	ENSG00000124787
Uniprot IDs		O95059	A0A087X1N3 O75818
PDB IDs		6AHR 6AHU	6AHR 6AHU 6AHV
Enriched GO Terms of Interacting Partners?
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