CNOT4 and RBM15

Number of citations of the paper that reports this interaction (PubMedID 26575292)
42

Data Source:
BioGRID (unspecified method)

		CNOT4	RBM15
Description		CCR4-NOT transcription complex subunit 4	RNA binding motif protein 15
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol CCR4-NOT Complex	Nucleus Nucleoplasm Nuclear Speck Nuclear Membrane RNA N6-methyladenosine Methyltransferase Complex
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Megakaryocyte Differentiation Protein Autoubiquitination	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Methylation Branching Involved In Blood Vessel Morphogenesis Positive Regulation Of Transcription Of Notch Receptor Target Dosage Compensation By Inactivation Of X Chromosome Thrombopoietin-mediated Signaling Pathway Negative Regulation Of Myeloid Cell Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Spleen Development Ventricular Septum Morphogenesis Placenta Blood Vessel Development
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Clostridioides difficle infection ( 33841421) Heel bone mineral density ( 30598549) Household income (MTAG) ( 31844048) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Meat-related diet ( 32066663) Numerical cognitive ability ( 31620175)
Interacting Genes		18 interacting genes: CNOT1 CNOT2 CNOT3 CNOT6 CNOT8 EP300 IL36RN KDM5C RBM15 UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2W	13 interacting genes: ABI1 CALCOCO2 CD2 CEP44 CLK1 CNOT4 DDX17 LZTS2 MAPK8 NAV2 PRMT1 SRPK2 TSPYL2
Entrez ID		4850	64783
HPRD ID		05369	05832
Ensembl ID		ENSG00000080802	ENSG00000162775
Uniprot IDs		A0A024R776 A0A024R781 A0A024R785 O95628	Q96T37
PDB IDs		1E4U 1UR6
Enriched GO Terms of Interacting Partners?
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