NMT1 and CAPN2

Number of citations of the paper that reports this interaction (PubMedID 16530191)
10

Data Source:
HPRD (in vivo)

		NMT1	CAPN2
Description		N-myristoyltransferase 1	calpain 2
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Plasma Membrane Extrinsic Component Of Membrane	Chromatin Nucleus Cytoplasm Mitochondrial Intermembrane Space Lysosome Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Dendrite Cortical Actin Cytoskeleton Pseudopodium Neuronal Cell Body Membrane Raft Extracellular Exosome Perinuclear Endoplasmic Reticulum
	Molecular Function	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding Myristoyltransferase Activity	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Cytoskeletal Protein Binding Cysteine-type Peptidase Activity Enzyme Binding Protein-containing Complex Binding
	Biological Process	In Utero Embryonic Development N-terminal Protein Myristoylation N-terminal Peptidyl-glycine N-myristoylation Regulation Of Rhodopsin Mediated Signaling Pathway Cellular Ketone Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Response To Hypoxia Blastocyst Development Proteolysis Myoblast Fusion Female Pregnancy Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Protein Autoprocessing Regulation Of Interleukin-6 Production Cellular Response To Interferon-beta Response To Hydrogen Peroxide Behavioral Response To Pain Regulation Of Cytoskeleton Organization Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Positive Regulation Of Neuron Death Positive Regulation Of Myoblast Fusion Positive Regulation Of Phosphatidylcholine Biosynthetic Process
Pathways		Late Phase of HIV Life Cycle Inactivation, recovery and regulation of the phototransduction cascade Activation, myristolyation of BID and translocation to mitochondria	Degradation of the extracellular matrix Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs		(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone
Diseases
GWAS		Asthma ( 31619474) Blood glucose levels ( 31928498) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Multisite chronic pain ( 33830993 31194737) Periventricular white matter hyperintensities ( 32517579) Plateletcrit ( 32888494) Pulse pressure ( 30578418) Systolic blood pressure ( 31928498 30578418) Walking pace ( 33128006) White matter hyperintensities ( 32358547) White matter hyperintensity volume ( 33293549)	Blood protein levels ( 30072576 29875488) Carotenoid levels (alpha-carotene) ( 28002826) Febrile seizures (MMR vaccine-related) ( 25344690) Gut microbiota relative abundance (Eubacterium belonging to family Erysipelotrichaceae) ( 33208821) Waist circumference ( 31170924)
Interacting Genes		15 interacting genes: ACBD6 ANXA13 ARL5A CABP1 CABP2 CAPN2 CSNK2A1 FYN GNAZ HPCA LYN MARCKS NOS3 SRC TP53	24 interacting genes: ATG5 ATXN3 BCL2 BID CAPNS1 CAPNS2 CASP9 CDK5R1 DUX4 F2RL1 GAS2 GRK2 KNG1 MAPK1 MAPT MTDH NFKBIA NMT1 PBXIP1 PTPN1 PTPRN TNS1 TUBA4A ZFYVE21
Entrez ID		4836	824
HPRD ID		01187	00254
Ensembl ID		ENSG00000136448	ENSG00000162909
Uniprot IDs		P30419	B4DN77 P17655 Q59EF6
PDB IDs		1RXT 3IU1 3IU2 3IWE 3JTK 4C2Y 4C2Z 5MU6 5NPQ 5O6H 5O6J 5O9S 5O9T 5O9U 5O9V 5UUT 6EHJ 6F56 6FZ2 6FZ3 6FZ5 6PAV 6QRM 6SJZ 6SK2 6SK3 6SK8 6SKJ	1KFU 1KFX 2NQA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?