NME3 and HTR2A

Number of citations of the paper that reports this interaction (PubMedID 16537434)
18

Data Source:
HPRD (two hybrid)

		NME3	HTR2A
Description		NME/NM23 nucleoside diphosphate kinase 3	5-hydroxytryptamine receptor 2A
Image
GO Annotations	Cellular Component	Cytosol	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Caveola Axon Dendrite Cytoplasmic Vesicle Neuronal Cell Body Dendritic Shaft Cell Body Fiber G Protein-coupled Serotonin Receptor Complex Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Gq/11-coupled Serotonin Receptor Activity Virus Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity Identical Protein Binding Protein-containing Complex Binding Serotonin Binding 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Apoptotic Process	Temperature Homeostasis Cellular Calcium Ion Homeostasis G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Phospholipase C-activating Serotonin Receptor Signaling Pathway Serotonin Receptor Signaling Pathway Chemical Synaptic Transmission Aging Memory Cell Death Positive Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Positive Regulation Of Phosphatidylinositol Biosynthetic Process Regulation Of Dopamine Secretion Phosphatidylinositol 3-kinase Signaling Artery Smooth Muscle Contraction Urinary Bladder Smooth Muscle Contraction Sleep Negative Regulation Of Potassium Ion Transport Positive Regulation Of MAP Kinase Activity Protein Localization To Cytoskeleton Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Glycolytic Process Positive Regulation Of Vasoconstriction Viral Entry Into Host Cell Behavioral Response To Cocaine Positive Regulation Of Peptidyl-tyrosine Phosphorylation Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of ERK1 And ERK2 Cascade G Protein-coupled Serotonin Receptor Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis
Pathways		Interconversion of nucleotide di- and triphosphates	Serotonin receptors G alpha (q) signalling events
Drugs			Ziprasidone Methysergide Cabergoline Zolmitriptan Amitriptyline Olanzapine Clozapine Mirtazapine Loxapine Remoxipride Promazine Cyproheptadine Imipramine Chlorpromazine Chlorpromazine Haloperidol Nortriptyline Amoxapine Lamotrigine Fenfluramine Lisuride Cisapride Fluphenazine Trazodone Thioridazine Ergotamine Apomorphine Paroxetine Paroxetine Trimipramine Risperidone Epinastine Propiomazine Minaprine Donepezil Flupentixol Cyclobenzaprine Mesoridazine Maprotiline Ergoloid mesylate Tegaserod Doxepin Nefazodone Desipramine Escitalopram Pergolide Bromocriptine Ketamine Quetiapine Aripiprazole Chlorprothixene Chlorprothixene Clomipramine Paliperidone Yohimbine Methotrimeprazine MMDA Midomafetamine Dimethyltryptamine 4-Bromo-2,5-dimethoxyphenethylamine Acepromazine Molindone Pipotiazine Thioproperazine Thiothixene Zuclopenthixol Aniracetam Fluspirilene Flibanserin Iloperidone HY10275 APD791 Pimavanserin Epicept NP-1 BL-1020 Cariprazine Lumateperone YKP-1358 Sertindole Mianserin Pizotifen Asenapine Ocaperidone Amisulpride Dotarizine Deramciclane Esmirtazapine Cinitapride Lurasidone Serotonin Perospirone Amperozide Butriptyline Cannabidiol Brexpiprazole Dosulepin Etoperidone Lorpiprazole Blonanserin Zotepine Pipamperone Setiptiline Dihydroergocornine Gilteritinib Sarpogrelate Eplivanserin Ketanserin Nelotanserin Ritanserin Tiapride Dihydroergocristine 2,5-Dimethoxy-4-ethylthioamphetamine N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine Medical Cannabis 5-methoxy-N,N-dimethyltryptamine Nabiximols Aripiprazole lauroxil
Diseases
GWAS			Blood protein levels ( 28240269) Cardiac hypertrophy ( 21348951) Parkinson disease and lewy body pathology ( 25663231) Serum 25-Hydroxyvitamin D levels ( 29325163) SjÃ¶gren's syndrome ( 28076899) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		13 interacting genes: APP DESI1 FXR1 FXR2 HTR2A JAM2 NME1 NME2 SGTA SGTB UBQLN1 UBQLN2 UBQLN4	25 interacting genes: ANKS1B ARF1 ARF6 CTSG DACH1 DIRAS3 DLG1 DLG4 EIF3F GLUL GNA11 GNAI1 GNAQ JAK2 MAP1A MRPL28 NDUFB10 NME3 NTRK3 PCDH9 PON2 PPP5C RFXAP RPS6KA3 SUGT1
Entrez ID		4832	3356
HPRD ID		03488	01638
Ensembl ID		ENSG00000103024	ENSG00000102468
Uniprot IDs		Q13232	P28223
PDB IDs		1ZS6	6A93 6A94 6WGT 6WH4 6WHA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?