NDUFB8 and ATP6V0D2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NDUFB8	ATP6V0D2
Description		NADH:ubiquinone oxidoreductase subunit B8	ATPase H+ transporting V0 subunit d2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Endoplasmic Reticulum	Lysosomal Membrane Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity	Protein Binding Proton Transmembrane Transporter Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly	Vacuolar Transport Vacuolar Acidification Regulation Of Macroautophagy Proton Transmembrane Transport
Pathways		Mitochondrial protein import Mitochondrial protein import Respiratory electron transport Complex I biogenesis	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		NADH	Tiludronic acid
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Palmitoleic acid (16:1n-7) levels ( 23362303)	Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		6 interacting genes: ATP6V0D2 CACNA1A EIF2B3 PFN2 PIM2 ZAP70	20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474
Entrez ID		4714	245972
HPRD ID		11886	16522
Ensembl ID		ENSG00000166136	ENSG00000147614
Uniprot IDs		O95169	A0A024R991 Q8N8Y2
PDB IDs		5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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