ATP6V0D2 and PHF12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATP6V0D2	PHF12
Description		ATPase H+ transporting V0 subunit d2	PHD finger protein 12
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Nucleus Nucleoplasm Sin3 Complex Transcription Repressor Complex Sin3-type Complex
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity	Transcription Corepressor Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Vacuolar Transport Vacuolar Acidification Regulation Of Macroautophagy Proton Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474	8 interacting genes: ATP6V0D2 BRCA1 H3-4 HDAC1 MORF4L1 NUFIP2 SHANK3 SIN3A
Entrez ID		245972	57649
HPRD ID		16522	15123
Ensembl ID		ENSG00000147614	ENSG00000109118
Uniprot IDs		A0A024R991 Q8N8Y2	C9J9G2 Q96QT6
PDB IDs			2L9S 2LKM
Enriched GO Terms of Interacting Partners?
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