NDUFB6 and FBN2

		NDUFB6	FBN2
Description		NADH:ubiquinone oxidoreductase subunit B6	fibrillin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Membrane	Microfibril Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial ATP Synthesis Coupled Electron Transport	Anatomical Structure Morphogenesis Embryonic Limb Morphogenesis Positive Regulation Of Bone Mineralization Sequestering Of TGFbeta In Extracellular Matrix Camera-type Eye Development Positive Regulation Of Osteoblast Differentiation Embryonic Eye Morphogenesis Bone Trabecula Formation
Pathways		Respiratory electron transport Complex I biogenesis	Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs		NADH	Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Immune response to smallpox vaccine (IL-6) ( 22610502)	Atrial fibrillation ( 29892015) Beard thickness ( 26926045) Brain morphology (MOSTest) ( 32665545) Breastfeeding duration ( 25475840) Central corneal thickness ( 32528159) Cortical surface area (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Height ( 21998595 31562340) Heschl's gyrus morphology ( 25130324) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29617998) Medication use (beta blocking agents) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Multiple system atrophy ( 27629089) Night sleep phenotypes ( 27126917) Obesity (extreme) ( 19553259) Pulse pressure ( 27841878 30578418) Refractive error ( 32231278) Response to fenofibrate (total cholesterol levels) ( 27002377) Severe aplastic anemia ( 32004448) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 32771030) Systolic blood pressure ( 28135244 27841878 30578418) Temperament ( 22832960) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		4 interacting genes: APP CREB3 ERGIC3 FBN2	22 interacting genes: CMBL CSF2 DPYSL5 DUSP5 ELN FBN1 FDPS ITGA2 LTBP1 MATN2 MFAP2 MFAP5 NDUFB6 NRG2 RNF14 SEMA3F SIRPA SLC27A6 SMAD2 SNRPB TRIM24 UBE2B
Entrez ID		4712	2201
HPRD ID		04504	00416
Ensembl ID		ENSG00000165264	ENSG00000138829
Uniprot IDs		A0A087WZX2 O95139	P35556
PDB IDs		5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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