NACA and APLP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NACA	APLP1
Description		nascent polypeptide associated complex subunit alpha	amyloid beta precursor like protein 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Nascent Polypeptide-associated Complex	Basement Membrane Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Unfolded Protein Binding	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	Protein Targeting To Membrane	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Extracellular Matrix Organization Forebrain Development Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs			Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Asthma ( 31619474) Atrial fibrillation ( 30061737 29892015) Diastolic blood pressure ( 30224653) JT interval ( 29874175) QRS duration ( 30012220)	Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		17 interacting genes: APLP1 CCDC90B FADD FOS FUNDC2 IGSF21 JUN LRIF1 MDM2 PPP1R18 PTEN SMYD1 SPP1 TBP TXLNA UCHL5 ZHX1	43 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 ERBB2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24
Entrez ID		4666	333
HPRD ID		03137	00102
Ensembl ID		ENSG00000196531	ENSG00000105290
Uniprot IDs		A0A024RB41 Q13765	P51693
PDB IDs		3LKX 3MCB 3MCE	3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA
Enriched GO Terms of Interacting Partners?
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