MUC1 and PPIF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MUC1	PPIF
Description		mucin 1, cell surface associated	peptidylprolyl isomerase F
Image
GO Annotations	Cellular Component	Chromatin Extracellular Space Nucleus Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Vesicle Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Permeability Transition Pore Complex Mitochondrial Matrix Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding P53 Binding Transcription Coregulator Activity Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding
	Biological Process	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Transcription By Competitive Promoter Binding Negative Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator	Protein Peptidyl-prolyl Isomerization Response To Ischemia Protein Folding Apoptotic Mitochondrial Changes Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of Necrotic Cell Death Negative Regulation Of ATPase Activity Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Necroptotic Process Cellular Response To Hydrogen Peroxide Cellular Response To Arsenic-containing Substance Cellular Response To Calcium Ion Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Phosphorylation Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family Interleukin-4 and Interleukin-13 signaling O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs		TG4010	Cyclosporine Proline Triglyme Coumarin 120
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908 21102463) Estimated glomerular filtration rate ( 31015462) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric cancer ( 26098866 26129866 31383772) Gout ( 31578528) Inflammatory bowel disease ( 28067908) Magnesium levels ( 20700443 25886283 26058915) Non-cardia gastric cancer ( 26701879) Serum magnesium levels ( 29093028) Serum uric acid levels ( 30993211 29403010) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin-to-creatinine ratio ( 26631737) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)	Blood protein levels ( 30072576) Height ( 20881960 31562340) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean platelet volume ( 32888494) Metabolite levels ( 23823483) Triglyceride levels ( 32203549)
Interacting Genes		146 interacting genes: ABL1 ADAM33 ADGRB3 ADGRL2 ADIPOQ ANKRD46 APC APOA2 APP AQP1 AQP2 AQP3 ARV1 BCL2L2 BMI1 BRICD5 BTN2A2 C14orf180 C1GALT1 C2 C2CD2L C3orf52 CACNG1 CCDC167 CD47 CD53 CD68 CLDN19 CLDN6 CLDND2 CMTM7 COL8A2 CSGALNACT2 CTNNB1 CTNND1 CTSA CXCL16 CXCL9 CYB5B CYP4F2 E2F2 EDDM3B EGFR EMC6 EMP3 ENTPD3 ERBB2 ERBB3 ERBB4 ERG28 ESR1 EZH2 GALE GALNT1 GALNT10 GALNT12 GALNT15 GALNT2 GALNT4 GAST GDNF GOLT1B GPR108 GRB2 GSK3B HHATL HSP90AA1 HSPA4 ICMT IKBKE INSIG2 ITGAM JUP LCK LTB4R2 LYN MAL2 MALL MARCHF2 MFSD5 MIP MYADM NDUFA3 NEU1 NINJ1 NINJ2 NKG7 NUP62 OAZ1 OR10AG1 OSGEP PAQR6 PKLR PLN PLP1 PLPP6 PNLIPRP1 PPARG PPIF PRKCD PSMB4 RFT1 RFX5 RHD RPS24 SCAMP5 SELENOK SERP2 SFTPC SIGLEC1 SLC22A1 SLC30A8 SLC35B4 SLC35E4 SLC38A7 SMCO4 SMIM1 SOS1 SRC SYT13 TECR TFB2M THBD TM6SF2 TMEM11 TMEM120B TMEM121 TMEM128 TMEM147 TMEM14A TMEM14C TMEM187 TMEM229B TMEM243 TMEM86A TMEM86B TMEM97 TMEM98 TNFRSF10B TP53 TRAM1L1 UNC50 VAMP5 VKORC1 ZAP70 ZDHHC21	19 interacting genes: ABI2 AGTRAP ARFIP2 BANP CIDEB CMTM5 FAM25A FAM25C FAM25G FKBP7 MAGEA11 MUC1 PRB3 SERPINB5 SLC25A4 SYP SYPL1 VDAC1 YIF1A
Entrez ID		4582	10105
HPRD ID		01152	06839
Ensembl ID		ENSG00000185499	ENSG00000108179
Uniprot IDs		A0A087X0L2 A0A087X2A4 A0A0A0MRB3 A0A0C4DGW3 A0A384NPK6 A5YRU5 A5YRU7 A5YRV0 A5YRV2 A6ZID6 A6ZID7 A6ZIE4 A6ZIE6 B6ECB3 P15941 Q7Z538 Q7Z551	A0A024QZS4 P30405
PDB IDs		1SM3 2ACM 2FO4 5T6P 5T78 6FZQ 6FZR 6KX1 6TGG	2BIT 2BIU 2Z6W 3QYU 3R49 3R4G 3R54 3R56 3R57 3R59 3RCF 3RCG 3RCI 3RCK 3RCL 3RD9 3RDA 3RDB 3RDC 4J58 4J59 4J5A 4J5B 4J5C 4J5D 4J5E 4O8H 4O8I 4XNC 4ZSC 4ZSD 5A0E 5CBT 5CBU 5CBV 5CBW 5CCN 5CCQ 5CCR 5CCS 6R8L 6R8O 6R8W 6R9S 6R9U 6R9X 6RA1 6Y3E 6YBM
Enriched GO Terms of Interacting Partners?
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